Karim Abdelhalim

Learn More
We present a fully differential 128-channel integrated neural interface. It consists of an array of 8 X 16 low-power low-noise signal-recording and generation circuits for electrical neural activity monitoring and stimulation, respectively. The recording channel has two stages of signal amplification and conditioning with and a fully differential 8-b(More)
A 3D microsystem for multi-site penetrating extracellular neural recording from the brain is presented. A 16 16-channel neural recording interface integrated prototype fabricated in 0.35 m CMOS occupies 3.5 mm 4.5 mm area. Each recording channel dissipates 15 W of power with input-referred noise of 7 over 5 kHz bandwidth. A switched-capacitor delta read-out(More)
An ultra wideband (UWB) 64-channel responsive neural stimulator system-on-chip (SoC) is presented. It demonstrates the first on-chip neural vector analyzer capable of wirelessly monitoring magnitude, phase and phase synchronization of neural signals. In a closed-loop, abnormal phase synchrony triggers the programmable-waveform biphasic current-mode neural(More)
We present a 320-channel active probe for high-spatial-resolution neuromonitoring and responsive neurostimulation. The probe comprises an integrated circuit (IC) cell array bonded to the back side of a pitch-matched microelectrode array. The IC enables up to 256-site neural recording and 64-site neural stimulation at the spatial resolution of 400 μ m and(More)
We present a compact current mode stimulator for utilization in neural stimulation arrays. The stimulator is implemented in a 0.35μm CMOS technology and occupies an area of 50μm×400μm. The memory in every current driver allows for simultaneous stimulation on multiple active channels when used as part of an array of stimulators. Circuit reuse in the(More)
A system-on-chip (SoC) neural recording interface with 64 channels, 64 16-tap programmable mixed-signal FIR filters and a fully integrated 915 MHz OOK/FSK PLL-based wireless transmitter is presented. Each recording channel has a fully differential amplifier with 54 dB gain and utilizes a tunable low-distortion subthreshold MOS-resistor to reject DC offsets(More)
Abstract— A system-on-chip (SoC) neural recording interface with 64 channels, 64 16-tap programmable mixed-signal FIR filters and a fully integrated 915MHz OOK/FSK closed-loop wireless transmitter is presented. Each recording channel has a fully differential amplifier with 54dB of gain and utilizes a tunable low-distortion subthreshold MOS-resistor to(More)
A low-power VLSI processor architecture that computes in real time the magnitude and phase-synchronization of two input neural signals is presented. The processor is a part of an envisioned closed-loop implantable microsystem for adaptive neural stimulation. The architecture uses three CORDIC processing cores that require shift-and-add operations but no(More)
We present a fully differential 128-channel integrated neural interface. It consists of an array of 8×16 lowpower low-noise signal recording and generation channels for electrical neural activity monitoring and stimulation, respectively. The recording channel has two stages of signal amplification and conditioning with a programmable gain of 54dB to 73dB,(More)