Kari McGuinness

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The ideal form of fixation for displaced, extra-articular fractures of the distal tibia remains controversial. In the UK, open reduction and internal fixation with locking-plates and intramedullary nailing are the two most common forms of treatment. Both techniques provide reliable fixation but both are associated with specific complications. There is(More)
Patients in clinical practice and participants in clinical trials are warned about side effects that may result from their treatment. Such warnings could lead to placebo-induced side effects if they create an expectation of these effects. We used an experimental model to test this possibility. Undergraduates reporting sleep difficulty received placebo(More)
OBJECTIVE The purpose of this study was to determine the prevalence and microbiologic characteristics of genital ulcer disease in a population of human immunodeficiency virus-infected women. STUDY DESIGN A retrospective cohort study was performed in university-affiliated, hospital-based women's human immunodeficiency virus clinics. A total of 307 women(More)
Propofol in a 1% emulsion was used to induce anaesthesia in 20 female patients premedicated with diazepam (10 mg). A dose of 2.5 mg kg-1 produced a rapid loss of consciousness and only minor excitatory effects. Discomfort during the injection was not severe. Cardiovascular changes included a fall in blood pressure similar to that which occurs with other(More)
Intra-operative, peri-articular injection of local anaesthesia is an increasingly popular way of controlling pain following total knee replacement. At the same time, the problems associated with allogenic blood transfusion have led to interest in alternative methods for managing blood loss after total knee replacement, including the use of(More)
A randomized study involving 60 healthy patients was performed to examine the induction characteristics and the possible interactions between propofol 2.5 mg/kg or thiopentone 4 mg/kg and three neuromuscular blocking agents, suxamethonium, atracurium and vecuronium. The time of onset to maximum blockade, the degree of blockade and the duration of blockade(More)
OBJECTIVE To report the experience with state-mandated voluntary newborn human immunodeficiency virus (HIV) screening in a large university hospital. METHODS Retrospective analysis of delivery records and newborn HIV screening data for infants born between May 4, 1996, and January 31, 1997. RESULTS Of 3111 women, 40% had HIV testing during pregnancy,(More)
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