Kari Klungsøyr

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BACKGROUND Attention-deficit/hyperactivity disorder (ADHD) is a prevalent and disabling lifespan disorder, but little is yet known about risk factors for ADHD persisting beyond adolescence. The present study investigates the association between pregnancy and birth complications and ADHD in adulthood. METHODS We used data from the Medical Birth Registry of(More)
OBJECTIVE To assess the association of pre-eclampsia with later cardiovascular death in mothers according to their lifetime number of pregnancies, and particularly after only one child. DESIGN Prospective, population based cohort study. SETTING Medical Birth Registry of Norway. PARTICIPANTS We followed 836,147 Norwegian women with a first singleton(More)
OBJECTIVE To assess the public health consequences of the rise in multiple births with respect to congenital anomalies. DESIGN Descriptive epidemiological analysis of data from population-based congenital anomaly registries. SETTING Fourteen European countries. POPULATION A total of 5.4 million births 1984-2007, of which 3% were multiple births. (More)
BACKGROUND Hypospadias is a common congenital malformation. The prevalence of hypospadias has a large geographical variation, and recent studies have reported both increasing and decreasing temporal trends. It is unclear whether hypospadias prevalence is associated with maternal age. AIM To analyze the prevalence and trends of total hypospadias, isolated(More)
BACKGROUND While international variations in overall cesarean delivery rates are well documented, less information is available for clinical sub-groups. Cesarean data presented by subgroups can be used to evaluate uptake of cesarean reduction policies or to monitor delivery practices for high and low risk pregnancies based on new scientific evidence. We(More)
Perfluoroalkyl substances (PFAS) are persistent and ubiquitous environmental contaminants, and human exposure to these substances may be related to preeclampsia, a common pregnancy complication. Previous studies have found serum concentrations of PFAS to be positively associated with pregnancy-induced hypertension and preeclampsia in a population with high(More)
OBJECTIVES To explore utilisation patterns of asthma medication before, during and after pregnancy as recorded in seven European population-based databases. DESIGN A descriptive drug utilisation study. SETTING 7 electronic healthcare databases in Denmark, Norway, the Netherlands, Italy (Emilia Romagna and Tuscany), Wales, and the Clinical Practice(More)
AIM To explore antidiabetic medicine prescribing to women before, during and after pregnancy in different regions of Europe. METHODS A common protocol was implemented across seven databases in Denmark, Norway, The Netherlands, Italy (Emilia Romagna/Tuscany), Wales and the rest of the UK. Women with a pregnancy starting and ending between 2004 and 2010,(More)
OBJECTIVE To assess the availability of obstetric institutions, the risk of unplanned delivery outside an institution and maternal morbidity in a national setting in which the number of institutions declined from 95 to 51 during 30 years. DESIGN Retrospective population-based, three cohorts and two cross-sectional analyses. SETTING Census data,(More)
BACKGROUND Prenatal inflammatory mechanisms may play a role in the pathogenesis of psychiatric disorders and could be relevant for attention-deficit/hyperactivity disorder (ADHD). We investigated maternal chronic somatic diseases with immune components as possible risk factors for ADHD in offspring. METHODS We performed a population-based nested(More)