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  • Kari Alitalo
  • Medicine
  • Nature Medicine
  • 2011 (First Publication: 1 November 2011)
  • Blood vessels form a closed circulatory system, whereas lymphatic vessels form a one-way conduit for tissue fluid and leukocytes. In most vertebrates, the main function of lymphatic vessels is toContinue Reading
  • Arja Kaipainen, Jaana Korhonen, +5 authors Kari Alitalo
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences…
  • 1995 (First Publication: 11 April 1995)
  • We have recently cloned the human fms-like tyrosine kinase 4 gene FLT4, whose protein product is related to two vascular endothelial growth factor receptors FLT1 and KDR/FLK1. Here the expression ofContinue Reading
  • Sebastian F. Schoppmann, Peter Birner, +7 authors Dontscho Kerjaschki
  • Biology, Medicine
  • The American journal of pathology
  • 2002 (First Publication: 1 September 2002)
  • Formation of lymphatic metastasis is the initial step of generalized spreading of tumor cells and predicts poor clinical prognosis. Lymphatic vessels generally arise within the peritumoral stroma,Continue Reading