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The average person in Hong Kong consumes fish or shellfish four or more times a week averaging about 60 Kg of fish per year. Even though the mean mercury level in store-bought Hong Kong fish was only 0.12 mg/kg, corroborating evidence is presented from numerous studies to support the view that mercury bioaccumulates. By the time a typical Hong Kong male(More)
Myelinated axons of white matter demonstrate prominent directional differences in water diffusion. We performed diffusion-weighted imaging on ten patients with head injury to explore the feasibility of using water diffusion anisotropy for quantitating diffuse axonal injury. We showed significant decrease in diffusion anisotropy indices in areas with or(More)
OBJECTIVE To determine whether multiple mailed patient reminders can produce an increase in the rate of diabetic retinal examinations (DRE) over that seen with a single reminder. RESEARCH DESIGN AND METHODS All diabetic members > or = 18 years who were enrolled in a large network-based health maintenance organization (HMO) in California from August 1996(More)
The objectives of this study were to validate a claims-based algorithm for identification of patients with newly diagnosed carcinoma of the breast and to optimize the algorithm. Claims data from all females aged 21 years or older who enrolled in a large California health maintenance organization during the study period from October 1, 1994 through March 31,(More)
BACKGROUND To improve asthma disease management, the National Asthma Education Program (NAEP) Expert Panel published Guidelines for the Diagnosis and Management of Asthma in 1991. OBJECTIVES To compare the current status of asthma disease management among patients in a large health maintenance organization with the NAEP guidelines and to identify the(More)
The objective of this study was to examine the compliance with the National Asthma Education Program (NAEP) guidelines among asthmatic members of eight health plans (regions) in seven states, as well as the factors related to the compliance. Information was gathered by means of a cross-sectional survey in a managed care environment. The participants were(More)
A key characteristic that distinguishes survival analysis from other areas in statistics is that survival data are usually censored. Censoring occurs when incomplete information is available about the survival time of some individuals. We define censoring through some practical examples extracted from the literature in various fields of public health. With(More)
AIMS/INTRODUCTION Type 2 diabetes is characterized by dysregulation of immunity, oxidative stress and reduced incretin effects. Experimental studies suggest that glucagon-like peptide (GLP-1) might have immunomodulating effects. We hypothesize that GLP-1 receptor agonist, exendin-4, might reduce inflammatory response in type 2 diabetes. MATERIALS AND(More)
BACKGROUND AND OBJECTIVES Primitive human hematopoietic cells contain higher levels of aldehyde dehydrogenase (ALDH) activity than their terminally differentiating progeny but the particular stages when ALDH levels change have not been well defined. The objective of this study was to compare ALDH levels among the earliest stages of hematopoietic cell(More)
OBJECTIVES The purpose of this study was to identify factors related to pregnancy and childbirth that might be predictive of a patient's length of stay after delivery and to model variations in length of stay. METHODS California hospital discharge data on maternity patients (n = 499,912) were analyzed. Hierarchical linear modeling was used to adjust for(More)