Karen L. Stavnes

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Two experiments were conducted in which inbred C57BL/6J and DBA/2J mice were trained in an active avoidance jump-up task under distributed practice conditions at a variety of ages comprising a large part of their life-span. DBA/2J mice were found to be basically an escaping strain and exhibited little change in behavior as a function of age. C57BL/6J mice(More)
Intracranial injections of gamma-aminobutyric acid, norepinephrine and 5-hydroxytryptamine were found to protect DBA/2J, C57BL/6J and F1 hybrid mice against pentylenetetrazol-induced seizures. Similar treatments were also found to protect DBA/2J mice against audiogenic seizures. These results are in agreement with those reported in pharmacological(More)
Animal models of human aging problems are potentially of enormous value to gerontological research. Models of behavioral problems have not often lived up to their promise. This review examines one such model system, avoidance learning in aging rodents. This model system has become increasingly popular among behavioral gerontologists, yet it has not provided(More)
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