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  • Joanne S. Lymn, Mahendra K. Patel, Gerard F Clunn, Sarafina J. Rao, Karen L Gallagher, Alun D. Hughes
  • Biology, Medicine
  • Journal of cell science
  • 15 November 2002
  • Thrombospondin-1 is a large matricellular protein that acts as a pleiotropic growth factor for human vascular smooth muscle cells, and may play a role in the progression of vascular disease. AlthoughContinue Reading
  • Joanne S. Lymn, Sarafina J. Rao, +4 authors Alun D. Hughes
  • Biology, Medicine
  • Arteriosclerosis, thrombosis, and vascular…
  • 1 September 1999
  • Thrombospondin-1 (TSP-1) is a matricellular protein that is expressed in negligible amounts in normal blood vessels but is markedly upregulated in vascular injury. Although TSP-1 can act as aContinue Reading
    The class 1(A) phosphatidylinositol 3-kinase enzymes consist of a number of heterodimeric complexes of regulatory and catalytic subunits and have been implicated in a number of cellular responses.Continue Reading