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How pseudouridylation (Ψ), the most common and evolutionarily conserved modification of rRNA, regulates ribosome activity is poorly understood. Medically, Ψ is important because the rRNA Ψ synthase, DKC1, is mutated in X-linked dyskeratosis congenita (X-DC) and Hoyeraal-Hreidarsson (HH) syndrome. Here, we characterize ribosomes isolated from a yeast strain(More)
OBJECTIVE To gain a better understanding of the level of literacy in information technology (IT) across the dental team working within primary care in Scotland, thus allowing appropriate planning of education and training for effective use of IT. DESIGN A postal questionnaire survey of all dentists and dental care professionals (DCPs) within primary care(More)
The study objective was to gain a better understanding of the level of literacy in information technology across the dental team within Scotland, thus allowing appropriate planning of education and training for effective use of information technology. In May 2004 a postal questionnaire survey was undertaken of all dentists (2679) and professionals(More)
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