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Improving the translation of basic research into the clinic is fast becoming a priority not just in the US but also in Europe. In the US, one of the biggest initiatives to enhance translational research is sponsored by the NIH through its Clinical and Translational Science Awards (CTSAs). The first CTSAs were awarded to 12 institutions in October last year,(More)
Research into the pathogenesis, prevention, and control of infectious and parasitic diseases remains a global priority, as these scourges continue to be a substantial cause of mortality and morbidity. The plethora of molecular tools that are now readily available has facilitated a genome-wide approach to studying the pathogenesis of such diseases, with(More)
generate truncated ETS proteins — rather than chimeric proteins — that are believed to drive prostate cancer development. Given the prevalence of prostate cancer (it accounts for approximately one-third of all cancer diagnoses in American men), researchers are seeking to determine whether TMPRSS2:ETS fusion genes provide an early detection diagnostic marker(More)