Karen Felsmann

Learn More
TNFα has been implicated in the pathogenesis of various inflammatory diseases. Different strategies to inhibit TNFα in patients with sepsis and chronic inflammatory conditions have shown contrasting outcomes. Although TNFα inhibitors are widely used in clinical practice, the impact of TNFα antagonism on white blood cell gene expression profiles during acute(More)
Septic syndroms and the associated perturbation of immune homeo — stasis represent a major health problem in intensive care settings. Aim of our development is a diagnostic tool for monitoring the post-operative host response to assess the risk of early infectious complications. The diagnostic application of an established RNA-biomarker panel from whole(More)
  • 1