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The magnitude and persistence of ethanol-induced increases in the latency of the P3 event-related potential from auditory stimuli were evaluated in 21 sons of alcoholic fathers (FHP) and 21 control sons of nonalcoholics (FHN) matched on demography and drinking history. The men were assessed at baseline, 70 min after imbibing a beverage, and 240 min after(More)
We demonstrate that phonological and articulatory impairments may occur at presentation or early in the course of Alzheimer's disease, contrary to claims that these aspects of language production are relatively preserved until the final stages of this disease. Six patients with pathologically confirmed Alzheimer's disease (AD) and four patients with(More)
OBJECTIVE To compare the pattern of cortical degeneration associated with different language deficits in cases of AD. METHODS Cases for detailed neuropathologic analysis (Patients 1 and 2) were selected because of their detailed clinical and neuropsychological assessments of language dysfunction in AD. Patient 1 had severe phonologic impairment with(More)
The research described in this article had 2 aims: to permit greater precision in the conduct of naming experiments and to contribute to a characterization of the motor execution stage of speech production. The authors report an exhaustive inventory of consonantal and postconsonantal influences on delayed naming latency and onset acoustic duration, derived(More)
Erreurs dans les phrases difficiles à prononcer (" tongue twisters ") ont é té influencées par la proéminence et la position de domaine initial dans la hiérarchie prosodique, soutenant l'explication d'une prosodie première des processus psycholinguistiques à l'oral. Les mots dans les phrases étaient moins susceptibles à l'erreur quand ils portaient(More)
We present an experiment investigation of the spoken single word production of two patients with nonfluent progressive aphasia. In Experiment 1, a task effect (reading > repetition > naming) suggested that phonological information available from task stimuli facilitated the patients' speech production; a length effect reflected the increased difficulty of(More)
We investigated sentence comprehension in 46 patients with probable minimal (very mild), mild, or moderate dementia of the Alzheimer type (DAT), comparing their performance on the Test for the Reception of Grammar (TROG), with that of 20 age- and education-matched controls. Performance on the TROG was generally related to dementia severity, independent of(More)
There exist few clinical assessments for limb apraxia, a disorder of learned, purposeful action, that enable clinicians to distinguish pathological from normal variance in limb praxis performance. We describe a theoretically motivated, comprehensive assessment battery for limb apraxia and present control comparison scores for 16 older healthy normal(More)
Three experiments with undergraduate student participants investigated whether high frequency nonword syllables of English and non-existing English syllables showed differential effects on response latency, accuracy, onset and rime duration or spectral measures of coarticulation in syllable naming tasks. Only the coarticulation data provided any support for(More)