Karen A Heslop

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BACKGROUND Variations in genes related to the dopaminergic pathway have been implicated in neuropsychiatric disorders such as schizophrenia, substance misuse, Alzheimer's disease and Post Traumatic Stress Disorder (PTSD). A single nucleotide polymorphism (SNP) (957C>T) and a deletion polymorphism (-141delC) in the DRD2 gene and a SNP (Taq1A) in a gene(More)
The European Respiratory Society (ERS) recognizes that there are an increasing number of national and international guidelines for the management of asthma, chronic obstructive pulmonary disease (COPD) and other chest diseases. Some of these guidelines recommend nebulizer use in specific circumstances, using either a jet nebulizer or an ultrasonic nebulizer(More)
The first British Thoracic Society guideline on pulmonary rehabilitation in adults is published in the accompanying Thorax supplement. Focusing on delivery of a quality pulmonary rehabilitation service, the evidenced-based guideline encompasses recommendations on the composition of the service, referral of patients and who benefits, the expected(More)
BACKGROUND COPD is a common progressive and debilitating medical condition. Mental health difficulties, such as anxiety and depression, have been reported in 25-50% of all patients with COPD. Interventions that reduce anxiety and depressive symptoms may affect COPD outcomes. Little data exists on the effect of managing these psychological difficulties in(More)
OBJECTIVE The mobile intensive treatment team (MITT) of the Valley Integrated Adult Mental Health Service in Brisbane, Australia, aims to provide services in the community to people with severe and persistent mental illness who have traditionally been heavily reliant on inpatient services (i.e. heavy service users). The MITT screening instrument (MITTSI)(More)
The European Respiratory Society (ERS) recognizes that there are an increasing number of national and international guidelines for the management of asthma, chronic obstructive pulmonary disease (COPD) and other chest diseases. Some of these guidelines recommend nebulizer use in speci® c circumstances, using either a jet nebulizer or an ultrasonic nebulizer(More)