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BACKGROUND Patients with atrial fibrillation (AF) often require temporary interruption of warfarin for an elective operation or invasive procedure. However, the safety and efficacy of periprocedural bridging anticoagulation with unfractionated heparin (UH) or low-molecular-weight heparin (LMWH) are still unclear. We evaluated the safety of periprocedural(More)
BACKGROUND Use of uninterrupted vitamin K antagonists (VKAs) during ablation of atrial fibrillation is superior to bridging with heparin. Few studies evaluated the use of uninterrupted new oral anticoagulants (NOACs) during ablation of atrial fibrillation. These studies are relatively small in size and mostly underpowered to show differences in the(More)
To the Editor: I read with great interest the study published by Dougherty et al demonstrating that moderately strenuous exercise significantly improved cardiovascular performance in persons with an implantable cardioverter-defibrillator. I commend the authors for their efforts. I believe the following issues should be clarified. First, the usual care group(More)
We commend the authors of the recently published ISAR-TRIPLE (Duration of Triple Therapy in Patients Requiring Oral Anticoagulation After Drug Eluting Stent Implantation) clinical trial on their efforts (1). The trial adds valuable information to the ongoing debate of antiplatelet and anticoagulation management in patients on chronic oral anticoagulation(More)
Background. Appropriate vancomycin dosing is important to ensure adequate bac-tericidal activity. The purpose of this study was to evaluate the impact of a CPOE on the achievement of early therapeutic vancomycin trough levels and clinical outcomes among adult patients admitted to surgical/medical wards and critical care units at the University of Arkansas(More)
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