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BACKGROUND AND PURPOSE An accurate diagnosis of a parotid gland mass is essential for adequate management. We determined the clinical efficacy of USCNB in diagnosing parotid gland masses by using cutting needles of different bores. METHODS We reviewed records for 40 benign and 13 malignant parotid lesions. USCNB was performed by using 14-20-gauge needles(More)
Nasopharyngeal carcinoma (NPC) is an Epstein Barr virus (EBV)-related malignancy in which the tumor microenvironment plays a pivotal role in tumor progression. Here, we developed two patient-derived xenograft (PDX) mouse lines from engrafted NPC metastatic tumors. Positive staining for EBV-encoded small RNAs confirmed that these tumors harbored EBV, and(More)
Primary parapharyngeal space neoplasms are rare among the tumors of the head and neck [1]. The majority of parapharyngeal space neoplasms are benign. Pleomorphic adenoma (PA) is the most common primary neoplasm arising in the parapharyngeal space (PPS) [2]. Benign para-pharyngeal PA typically is well-demarcated and displaces the adjacent structures without(More)
Differential overall survival of nasopharyngeal carcinoma (NPC) with different organ site metastases has been documented. Here, we attempted to determine the underlying mechanisms by assessing plasma and tumor tissue markers in relation to patient survival. Pretreatment plasma Epstein-Barr virus (EBV) DNA concentrations, cytokines and tissue macrophages,(More)
Children with sensorineural hearing loss (SNHL) often present to otolaryngologists before adolescence. Early diagnosis and correction of the cause of SNHL are important in speech and language development for young children [1]. Cochlear implantation is an effective treatment for selected patients with SNHL [2]. The presence of a functioning cochlear nerve(More)
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