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PURPOSE To determine if the topoisomerase I inhibitor Camptothecin (CPT) can induce apoptosis in vitro in a human nasopharyngeal carcinoma (NPC) cell line with low differentiation (CNE-2Z). METHODS The light microscopy, flow cytometry and agarose gel electrophoresis were used to examine the morphological changes, cell cycle distribution, hypodiploid cells(More)
Pseudouridine, mainly as a degradation product of transfer ribonucleic acid, has been shown to be excreted in abnormal amounts in the urine of patients with cancer and can be used as one of the potentially valuable tumor markers. In this paper, a method for the rapid determination of human urinary pseudouridine by HPCE is reported. We used a 24 cm x 25(More)
The level of urinary creatinine in clinic diagnosis is one of the useful index of renal function, and is often used as a reference of some biochemical substance determined in random urine. In this paper, a rapid multiple-injection capillary electrophoresis(CE) method for the determination of urinary creatinine is reported. A 36 cm x 50 microns coated(More)
A novel method based on cataluminescence (CTL) generated on the surface of nanosized Bi4MnO8 was proposed for direct determination of BTEX (benzene, toluene, ethyl benzene, xylenes) in air. The method showed high selectivity for BTEX at wavelength of 620 nm, satisfying activity at reaction temperature of 355°C and good stabiLity at air carrier flow(More)
Based on the phenomenon that each of chlorpromazine (CPZ), promethazine (PMZ), chlorpromazine sulfoxide (CPZSO) and promethazine sulfoxide (PMZSO) could enhance the electrochemiluminescence (ECL) intensity of tris(2,2'-bipyridyl) ruthenium, a novel and sensitive method was proposed for the simultaneous determination of CPZ, PMZ and their main metabolites(More)
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