Kaoru Konishi

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The development and aging of four brain midline structures--the pituitary gland, pons, cerebellar vermis, and corpus callosum--were studied. The dimensions and area of these structures were measured by means of midsagittal magnetic resonance imaging. The study group consisted of 94 patients newborn to 15 years old and 49 patients and seven volunteers 16-60(More)
Cerebral blood flow and P300, a long-latency, positive component of the scalp-recorded, event-related potential (ERP), were measured in 26 patients with multiple cerebral infarcts (mean age, 65.0 years). Compared with age-matched normal subjects, patients with multiple cerebral infarcts had significantly lower cortical blood flow values and had prolongation(More)
Normal development and maturation in pre- and postnatal periods were studied using MR imaging. For this purpose, we performed MR imaging at a postmenstrual age of 37-44 weeks in both low-risk preterm and fullterm infants and assessed the myelination pattern and the dimension of the pituitary gland, corpus callosum, pons and cerebellar vermis. There were no(More)
Normal brain maturation was evaluated with MR imaging of 36 neonate to 2-year-old patients. The myelination process in centrum semiovale was quantitatively assessed in 50 6-months- to 15-year-old children, and 40 adults aged 16-60 years. Imaging was performed with a 0.35 T superconducting MR unit using spin echo pulse sequences. On T1-weighted images, three(More)
Magnetic resonance imaging (MRI) was performed on five patients with infantile spasms who were treated with relatively low doses of adrenocorticotrophic hormone (ACTH) to study the extent of brain shrinkage induced by ACTH therapy. MRI prior to ACTH therapy revealed periventricular hyperintensity (PVH) areas and poor myelination in four patients. In one(More)
The event-related potential and motor reaction time were simultaneously recorded in 35 patients with Parkinson's disease (26 nondemented and nine demented) and 15 age-matched neurologically normal control subjects during the performance of visual discrimination tasks. There were no significant differences in either the latency or amplitude of the P300(More)
Local cerebral blood flow was measured in 10 high-risk infants with neonatal episodic neurological events at 41-44 post-conceptional weeks using N-isopropyl-p-[123I]iodoamphetamine (IMP) and single photon emission computed tomography (SPECT). In 5 of the 7 infants with normal neurological outcome, prominent cerebral perfusion was found in the basal ganglia,(More)
The laterality of head position, spontaneous finger movements, hand-face contact, and hand-mouth contact was studied in low-risk preterm infants of 31 to < 37 weeks postconceptional age (intrauterine + neonatal period at time of study). The head was predominantly turned towards the right side during the preterm period. Hand-mouth contact was more frequent(More)
Magnetic resonance imaging was performed in 9 preterm infants at 37-43 weeks postmenstrual age. They all were born at 26-35 weeks gestation. Myelination was graded according to its most cephalic location. Myelination pattern 2 (myelination observed in the posterior limb of the internal capsule and adjacent structures of the thalamus and lenticular nucleus)(More)
The development of posture in the prone and supine positions was studied longitudinally in 10 low risk preterm infants between 31 and 39 weeks' postmenstrual age whose subsequent neurological development at 18 months old was normal. The infants were observed from one week after birth until the expected date of delivery. All postures were analysed according(More)