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  • Lars Verschuren, Peter Y. Wielinga, +5 authors Teake Kooistra
  • Biology, Medicine
  • BMC Medical Genomics
  • 2013 (First Published: 1 December 2014)
  • BackgroundCardiac pathological hypertrophy is associated with a significantly increased risk of coronary heart disease and has been observed in diabetic patients treated with rosiglitazone whereasContinue Reading
  • Martine C Morrison, Petra Mulder, +7 authors Peter Y. Wielinga
  • Medicine
  • International Journal of Obesity
  • 2016 (First Published: 1 September 2016)
  • Background/Objectives:Non-alcoholic steatohepatitis (NASH) is a serious liver condition, closely associated with obesity and insulin resistance. Recent studies have suggested an important role forContinue Reading
  • Kanita Salic, Robert Kleemann, Cynthia Wilkins-Port, J. C. Mcnulty, Lars Verschuren, Melissa Palmer
  • Chemistry, Medicine
  • PloS one
  • 2019 (First Published: 24 June 2019)
  • Interruption of bile acid recirculation through inhibition of the apical sodium-dependent bile acid transporter (ASBT) is a promising strategy to alleviate hepatic cholesterol accumulation inContinue Reading
  • Martine C Morrison, Lars Verschuren, +17 authors Robert Kleemann
  • Medicine
  • Hepatology communications
  • 2018 (First Published: 1 December 2018)
  • Concerns have been raised about whether preclinical models sufficiently mimic molecular disease processes observed in nonalcoholic steatohepatitis (NASH) patients, bringing into question theirContinue Reading