Kanika Sharma

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Orexins/hypocretins heavily innervate the posterior division of the paraventricular nucleus of the thalamus (pPVT), which expresses both orexin receptor types. The pPVT is important for adaptations to repeated stress, particularly the ability to facilitate to novel stress after repeated stress exposure. Here, we examined how orexins acting in the pPVT(More)
OBJECTIVES To examine the primary risk factor for oral cancer in the US, smoking and tobacco use, among the specific US states that experienced short-term increases in oral cancer incidence and mortality. METHODS Population-based data on oral cancer morbidity and mortality in the US were obtained from the National Cancer Institute's (NCI) Surveillance,(More)
In Wireless Sensor Networks (WSNs), sensor nodes have limited battery power, so energy consumption is essential issue. Every sensor node can obtain its location information from GPS or other positioning system and send data to sink at any time. In this paper, comparison of the dynamic network topologies in Wireless Sensor Networks has been done. The(More)
An aqueous extract of human placenta exhibits strong gelatinase/collagenase activity in zymography. 2-D gel electrophoresis of the extract with gelatin zymography in the second dimension displayed a single spot, identified as ubiquitin-like component upon MALDI/TOF MS/MS analysis. Immunoblot indicated presence of ubiquitin and absence of collagenase in the(More)
Wireless sensor network is a network formed by large number of sensor nodes which are randomly distributed in some regions. There is an issue of limited power supply of node and in fact battery of node is infeasible in replacement. The Life time of wireless sensor network is very much dependent on the life of each sensor node. As node does the task of(More)
Indian cauliflower (Brassica oleracea var. botrytis L.; C genome) is highly susceptible to black rot caused by Xanthomonas campestris pv. campestris (Pam.) Dowson. Till now no durable resistance genes have been identified in C genome of Brassica. Two B. carinata genotypes, NPC-9 and HCA-6 were found highly resistant to Xcc race 1 and 4, most prevalent(More)
Olfaction poses one of the most complex ligand-receptor matching problems in biology due to the unparalleled multitude of odor molecules facing a large number of cognate olfactory receptors. We have recently deorphanized an olfactory receptor, TAAR13c, as a specific receptor for the death-associated odor cadaverine. Here we have modeled the(More)
Microspore culture technique is widely used in Brassicas for development of haploids and doubled haploids (DH) in breeding programmes and genetic studies. Indian cauliflower, a group of vegetable Brassica; with tolerance to higher temperature and moisture, has been selected in India for last 200 years. In India, cauliflowers are grown throughout the year in(More)
Noxa, a BH3-only pro-apoptotic BCL-2 family protein, causes apoptosis by specifically interacting with the anti-apoptotic protein MCL-1 to induce its proteasome-mediated degradation. We show here that the DNA damaging agents cisplatin and etoposide upregulate Noxa expression, which is required for the phosphorylation of MCL-1 at Ser64/Thr70 sites,(More)