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mRNP granules at adult central synapses are postulated to regulate local mRNA translation and synapse plasticity. However, they are very poorly characterized in vivo. Here, in Drosophila olfactory synapses, we present early observations and characterization of candidate synaptic mRNP particles, one of which contains a widely conserved, DEAD-box helicase,(More)
In confocal microscopy imaging, target objects are labeled with fluorescent markers in the living specimen, and usually appear as spots in the observed images. Spot detection and analysis is therefore an important task but it is still heavily reliant on manual analysis. In this paper, a novel shape modeling algorithm is proposed for automating the detection(More)
In confocal microscopy imaging, the target objects are labeled with fluorescent markers in the living specimen, and usually appear as spots in the observed images. Spot detection and analysis is an important task for the biological studies from the observed images. However, while the spots have irregular sizes and positions due to the variant amount of(More)
Active contours are a well known segmentation toolkit and widely adopted in various forms for biological image analysis. Most techniques are commonly based on object geometry but overlapping regions cause severe problems to contour propagation. In this paper, we propose a novel active contour technique (“cellsnake”) for solving this problem(More)
The formations of various memories require the present of different specify mRNP in the neuron cells. The development of fluorescent proteins and high resolution fluorescence imaging allow the biologists to locate the mRNP in a living specimen by the co-localization of the differently labeled protein markers. However, the quantitative interpretation of the(More)
Atomic Force Microscopy (AFM) has been widely used in the material and life sciences and has enabled much progress in nanotechnology since it was invented. AFM relies on inter-atomic forces to form a topographical map of a sample surface. Depending on the surface type, it is possible to achieve atomic resolution. However, due to either the microscope design(More)
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