Joo-Young Im10
Pyung-Lim Han10
10Joo-Young Im
10Pyung-Lim Han
Learn More
alpha-Synuclein is a key protein in Parkinson's disease (PD) because it accumulates as fibrillar aggregates in pathologic hallmark features in affected brain regions, most notably in nigral dopaminergic neurons. Intraneuronal levels of this protein appear critical in mediating its toxicity, because multiplication of its gene locus leads to autosomal(More)
α-Synuclein (α-Syn) is a key protein that accumulates as hyperphosphorylated aggregates in pathologic hallmark features of Parkinson's disease (PD) and other neurodegenerative disorders. Phosphorylation of this protein at serine 129 is believed to promote its aggregation and neurotoxicity, suggesting that this post-translational modification could be a(More)
The transgenic mouse Tg2576 is widely used as a murine model of Alzheimer's disease (AD) and exhibits plaque pathogenesis in the brain and progressive memory impairments. Here we report that Tg2576 mice also have severe spinal cord deficits. At 10 months of age, Tg2576 mice showed a severe defect in the hindlimb extension reflex test and abnormal body(More)
Distributed shared memory (DSM) provides transparent network interface based on the memory abstraction. Furthermore, DSM gives us the ease of programming and portability. Also the advantages ooered by DSM include low network overhead, with no explicit operating system intervention to move data over network. With the advent of high-bandwidth networks and(More)
Alzheimer's disease (AD) is a progressive neurodegenerative disease caused by genetic and non-genetic factors. Most AD cases may be triggered and promoted by non-genetic environmental factors. Clinical studies have reported that patients with AD show enhanced baseline levels of stress hormones in the blood, but their physiological significance with respect(More)
This paper presents a human-robot interaction framework that outlines a general structure of future home service robots that are expected to assist humans in their home-based daily activities. We describe three interaction modules – multimodal, cognitive, and emotional interaction modules. Each module takes a different role in the process of human robot(More)
—This paper describes the ongoing development of a software framework for supporting interoperability and integration among heterogeneous network-based robotic development frameworks. We studied two of network based robotic software development frameworks named CAMUS framework and RT-Middleware. The CAMUS(Context-aware Middleware for URC Systems) is a(More)
BACKGROUND Recent studies have revealed that C-peptide induces smooth muscle cell proliferation and causes human atherosclerotic lesions in diabetic patients. The present study was designed to examine whether the basal C-peptide levels correlate with cardiovascular risk in type 2 diabetes mellitus (T2DM) patients. METHODS Data was obtained from 467(More)