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The state-of-the-art methods used for relation classification are primarily based on statistical machine learning, and their performance strongly depends on the quality of the extracted features. The extracted features are often derived from the output of pre-existing natural language processing (NLP) systems, which leads to the propagation of the errors in(More)
Dendritic cells (DCs) are able in tissue culture to phagocytose and present antigens derived from infected, malignant, and allogeneic cells. Here we show directly that DCs in situ take up these types of cells after fluorescent labeling with carboxyfluorescein succinimidyl ester (CFSE) and injection into mice. The injected cells include syngeneic splenocytes(More)
Traditional approaches to the task of ACE event extraction primarily rely on elaborately designed features and complicated natural language processing (NLP) tools. These traditional approaches lack generalization , take a large amount of human effort and are prone to error propagation and data sparsity problems. This paper proposes a novel event-extraction(More)
CD4(+)CD25(+)Foxp3(+) natural regulatory T cells (T reg cells) maintain self-tolerance and suppress autoimmune diseases such as type 1 diabetes and inflammatory bowel disease (IBD). In addition to their effects on T cells, T reg cells are essential for maintaining normal numbers of dendritic cells (DCs): when T reg cells are depleted, there is a(More)
In this paper, we present a novel method based on CRFs in response to the two special characteristics of " contextual dependency " and " label redundancy " in sentence sentiment classification. We try to capture the contextual constraints on sentence sentiment using CRFs. Through introducing redundant labels into the original sentimental label set and(More)
Classical dendritic cells (cDCs), monocytes, and plasmacytoid DCs (pDCs) arise from a common bone marrow precursor (macrophage and DC progenitors [MDPs]) and express many of the same surface markers, including CD11c. We describe a previously uncharacterized zinc finger transcription factor, zDC (Zbtb46, Btbd4), which is specifically expressed by cDCs and(More)
Two problems arise when using distant supervision for relation extraction. First, in this method, an already existing knowledge base is heuristically aligned to texts, and the alignment results are treated as labeled data. However, the heuristic alignment can fail, resulting in wrong label problem. In addition, in previous approaches , statistical models(More)
CD103(+) dendritic cells (DCs) in nonlymphoid tissues are specialized in the cross-presentation of cell-associated antigens. However, little is known about the mechanisms that regulate the development of these cells. We show that two populations of CD11c(+)MHCII(+) cells separated on the basis of CD103 and CD11b expression coexist in most nonlymphoid(More)
Community-based question answer (Q&A) has become an important issue due to the popularity of Q&A archives on the web. This paper is concerned with the problem of question retrieval. Question retrieval in Q&A archives aims to find historical questions that are semantically equivalent or relevant to the queried questions. In this paper, we propose a novel(More)
Peripheral immune tolerance is believed to be induced by the processing and presentation of self-tissues that die during physiologic tissue turnover. To examine the mechanism that mediates tolerance, we injected mice with dying syngeneic TAP(-/-) splenocytes loaded with small amounts of the protein antigen, ovalbumin (OVA). After ingestion and presentation(More)