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Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile canalicular membranes
The ezrin-radixin-moesin (ERM) family of proteins crosslink actin filaments and integral membrane proteins. Radixin (encoded by Rdx) is the dominant ERM protein in the liver of wildtype mice and isExpand
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Radixin deficiency causes deafness associated with progressive degeneration of cochlear stereocilia
Ezrin/radixin/moesin (ERM) proteins cross-link actin filaments to plasma membranes to integrate the function of cortical layers, especially microvilli. We found that in cochlear and vestibularExpand
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Effects of genetic backgrounds on hyperbilirubinemia in radixin-deficient mice due to different expression levels of Mrp3.
ERM (ezrin/radixin/moesin) proteins are organizers of apical actin cortical layer in general. We previously reported that the knockout of radixin resulted in Rdx(-/-) mice with displacement/loss ofExpand
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Hemobilia and cystic artery stump pseudoaneurysm associated with liver abscess after a laparoscopic cholecystectomy: Report of a case
A 63-year-old woman was admitted for cholecystitis and underwent a laparoscopic cholecystectomy (LC). She experienced abdominal pain and hemobilia 11 days after the LC. Angiography was performed butExpand
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Efficacy of transumbilical laparoscopic-assisted appendectomy for appendicitis: a four-year experience at a single center
PurposeTo compare the surgical outcomes after transumbilical laparoscopic-assisted appendectomy (TULAA) and open appendectomy (OA) at a single institution.MethodsWe compared the surgical outcomes forExpand
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Massive chronic irreducible rectal prolapse successfully treated with Altemeier’s procedure
Abstract The guideline for the treatment of rectal prolapse recommends that surgeons select appropriate surgical procedures individually based on each patient’s overall status. However, in cases ofExpand
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A novel procedure for introducing a large gauze into the corporeal cavity by using a slim trocar (the Tornado gauze procedure).
INTRODUCTION When a large gauze is needed during a single-incision surgery or reduced port surgery using slim (5-mm) trocars, the operation needs to be interrupted to introduce the gauze via anExpand
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Impact of UGT1A1 genotype on prognosis in Japanese advanced colorectal cancer patients treated by irinotecan-based regimens.
3525 Background: The influence of UGT1A1*6 and UGT1A1*28 on prognosis of irinotecan (IRI)-based regimens has been controversial, although UGT1A1 genotypes are risk factors for IRI-related toxicitiesExpand
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[The Case of a Long-Surviving Patient with Colorectal Neuroendocrine Carcinoma with Invasion of the Jejunum and Lymph Node Metastases after Operation].
A 44-year-old man presented to our hospital with high fever and right side ache. Laboratory data revealed the presence of inflammation. Enhanced CT of the abdomen revealed a 15 cm mass of theExpand
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[A patient with metachronous ovarian metastases of signet-ring cell carcinoma of the transverse colon showing long-term survival after surgery].
The patient was a 43-year-old female who consulted a local physician due primarily to lower abdominal pain. She was referred to our hospital for close evaluation and treatment. Since circumferentialExpand
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