Kanae Kobayashi

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This study assessed the endocrine pancreatic responses to liraglutide (0.9 mg once a day) during normal living conditions in Japanese patients with type 2 diabetes. The study included 14 hospitalized patients with type 2 diabetes. Meal tests were performed after improvement of glycemic control achieved by two weeks of multiple insulin injection therapy and(More)
Camptothecin is a monoterpenoid indole alkaloid that exhibits anti-tumor activity. In Ophiorrhiza pumila, production of camptothecin and its related alkaloids was high in the hairy roots, but not in the cell suspension culture derived from hairy roots. To identify the intermediates in camptothecin biosynthesis, expression of genes encoding tryptophan(More)
OBJECTIVE Recent studies have suggested that a difference in systolic blood pressure (SBP) between arms is associated with both vascular disease and mortality. The aim of this study was to investigate the relationship between a difference in SBP between arms and change in urinary albumin excretion or development of albuminuria in patients with type 2(More)
UNLABELLED Aims/Introduction:  Eicosapentaenoic acid (EPA) stimulates glucagon-like peptide-1 (GLP-1) secretion in mice. We investigated the relationship between serum EPA concentrations and the efficacy of dipeptidyl-peptidase IV (DPP-4) inhibitor in patients with type 2 diabetes. MATERIALS AND METHODS   Serum EPA concentrations were measured in 62(More)
OBJECTIVE Bilirubin has been recognized as an important endogeneous antioxidant. Previous studies reported that bilirubin could prevent atherosclerosis. The aim of this study was to investigate if serum bilirubin concentration could be a predictor for the development of albuminuria in patients with type 2 diabetes. MATERIALS AND METHODS We measured serum(More)
Chromogenic materials can change their optical properties in response to external stimuli, such as light irradiation [ 1–3 ] (photochromic materials), temperature change [ 4 , 5 ] (thermochromic materials), exposure to gas [ 6 , 7 ] (gaschromic materials), and the application of an electrical voltage [ 8–14 ] (electrochromic materials). Great interest has(More)
The scallop Patinopecten yessoensis is one of the major marine products in Hokkaido, Japan. As a result, approximately 200 000 tons per year of scallop shells is generated as industrial waste. Although scallop shells have been used as a source of CaCO3 and calcium, and as material for desulfurization, their further utilization is currently desirable. The(More)
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