Kan Wu

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Batching plays an important role in performance evaluation of manufacturing systems. Three types of batching are commonly seen: transfer batches, parallel batches and serial batches. To model the batching behavior correctly, a comprehensive classification of batching is proposed. Eight types of batching behavior are classified and corresponding queueing(More)
Performance evaluation plays a key role in manufacturing system design and productivity improvement. Characterizing performance objectively is the first step. Inspired by the underlying structure of tandem queues, we have derived an approximate model to characterize the system performance. The model decomposes system queue time and variability into(More)
Changeover setups are induced by switching manufacturing processes among products. They commonly exist in flexible manufacturing systems. Modeling their queue time impact correctly is of fundamental importance in evaluating the performance of production systems. In this paper, the mean queue time approximation models are proposed based on the properties of(More)
Queueing theory is a well-known method for evaluating the performance of manufacturing systems. When we want to analyze the performance of a single machine, M/M/1 queues or approximations of G/G/1 queues often are considered a proper choice. However, due to the complex nature of interruptions in manufacturing, the appropriate model should be selected(More)
In this paper, we study a MAP/PH/1 queue with two classes of customers and discretionary priority. There are two stages of service for the low-priority customer. The server adopts the preemptive priority discipline at the first stage and adopts the nonpreemptive priority discipline at the second stage. Such a queueing system can be modelled into a(More)
Contemporary technology for Product Lifecycle Management (PLM) integrates computer aided design (CAD) and engineering analysis (CAE) to support rapid, distributed, team-oriented product data development and management, including high fidelity simulation on demand. This technology potentially provides a platform for creating a new generation of factory(More)
Afatinib is a second-generation of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor and has shown a significant clinical benefit in non-small cell lung cancer (NSCLC) patients with EGFR-activating mutations. However, the potential therapeutic effects of afatinib combining with other modalities, including ionizing radiation (IR), are not(More)