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  • Devadoss J. Samuvel, Kamala P. Sundararaj, Alena Nareika, Maria Lopes-Virella, Yan Huang
  • Medicine, Biology
  • The Journal of Immunology
  • 2009 (First Publication: 15 February 2009)
  • It has been shown that lactate induces insulin resistance. However, the underlying mechanisms have not been well understood. Based on our observation that lactate augments LPS-stimulated inflammatoryExpand
  • Serap Koybasi, Can E. Senkal, +9 authors Besim Ogretmen
  • Biology, Medicine
  • Journal of Biological Chemistry
  • 2004 (First Publication: 22 October 2004)
  • In this study, endogenous long chain ceramides were measured in 32 human head and neck squamous cell carcinoma (HNSCC) and 10 nonsquamous head and neck carcinoma tumor tissues, as compared withExpand
  • Kamala P. Sundararaj, Rachel E Wood, +6 authors Besim Ogretmen
  • Medicine, Biology
  • Journal of Biological Chemistry
  • 2004 (First Publication: 13 February 2004)
  • Ceramide has been demonstrated as one of the upstream regulators of telomerase activity. However, the role for ceramide in the control of telomere length remains unknown. It is shown here thatExpand
  • Devadoss J. Samuvel, Kamala P. Sundararaj, Yan-chun Li, Maria Lopes-Virella, Yan Huang
  • Medicine, Biology
  • The Journal of Biological Chemistry
  • 2009 (First Publication: 10 December 2009)
  • Although it has been reported that osteopontin, a matrix glycoprotein and proinflammatory cytokine, mediates obesity-induced adipose tissue macrophage infiltration and insulin resistance, it remainsExpand
  • Kamala P. Sundararaj, Devadoss J. Samuvel, Yan-chun Li, John J. Sanders, Maria Lopes-Virella, Yan Huang
  • Medicine, Biology
  • Journal of Biological Chemistry
  • 2009 (First Publication: 15 May 2009)
  • Matrix metalloproteinases (MMPs) play a key role in periodontal disease. Although it is known that macrophages and fibroblasts are co-localized and express MMPs in the diseased periodontal tissue,Expand
  • Kamala P. Sundararaj, Devadoss J. Samuvel, +5 authors Yan Huang
  • Medicine, Biology
  • Journal of leukocyte biology
  • 2008 (First Publication: 1 October 2008)
  • Matrix metalloproteinase (MMP) plays a crucial role in periodontal disease and is up-regulated by oral Gram-negative, pathogen-derived LPS. In this study, we reported that simvastatin, aExpand
  • Coleen M. Cole, Kamala P. Sundararaj, +5 authors Y. Huang
  • Medicine
  • Journal of periodontal research
  • 2008 (First Publication: 1 December 2008)
  • BACKGROUND AND OBJECTIVE Epidemiological studies have established that patients with diabetes have increased prevalence and severity of periodontal disease. However, the periodontal expression ofExpand
  • Alena Nareika, Kamala P. Sundararaj, Yeong-Bin Im, Bryan A Game, Maria Lopes-Virella, Yan Huang
  • Medicine
  • Atherosclerosis
  • 2009 (First Publication: 1 February 2009)
  • Recent diabetes control and complications trial and epidemiology of diabetes interventions and complications (DCCT/EDIC) and other clinical studies have reported that glucose control in patients withExpand
  • Yanchun Li, Devadoss J. Samuvel, Kamala P. Sundararaj, Maria Lopes-Virella, Yan Huang
  • Biology, Medicine
  • Journal of cellular biochemistry
  • 2010 (First Publication: 1 May 2010)
  • Matrix metalloproteinases (MMPs) play a pivotal role in tissue remodeling and destruction in inflammation-associated diseases such as cardiovascular disease and periodontal disease. Although it isExpand