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BACKGROUND Castleman's disease (CD), a rare condition of uncertain etiology, involves a massive proliferation of lymphoid tissues and typically presents as mediastinal masses. We describe a patient with CD who presented with diffuse adenopathy involving the inguinal, paratracheal, retroperitoneal, axillary, and pelvic regions. CASE PRESENTATION Case(More)
The activated partial thromboplastin time test measures the integrity of the intrinsic clotting system. The sensitivity of this test to Fletcher factor deficiency is dependent upon the particular protocol and reagents utilized in the test system. The case report presented here demonstrates conflicting laboratory results obtained for a patient who had(More)
A 34-year-old patient, with severe factor VIII deficiency (anti-hemophilic factor deficiency) and inhibitor against factor VIII, underwent a phacoemulsification with posterior capsulatomy and thermal iridectomy under general anesthesia. FEIBA (Factor Eight Inhibitor Bypassing Activity) was used to achieve hemostasis. The surgical procedure was successful(More)
A 56 year old white man with psoriasis without serologic evidence of systemic lupus erythematosus was found to have a circulating anticoagulant against Factor XI with a low activity of Factor IX which could not be fully explained. The activity of the circulating anticoagulant was not potentiated on incubation after addition of normal plasma and it was still(More)
This is a report of haemoglobin E trait in a black American family with no known Asian ancestory. The father appears to be heterozygous for both haemoglobin E and alpha-thalassaemia. The mother is normal both clinically and haematologically. These children carry Hb E trait alone. The youngest son has a normal haemoglobin pattern and appears to have(More)