Kallen E. Tsikalas

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Upon exposure to follicle-stimulating hormone (FSH), the gonadotropin-responsive Sertoli cell expresses increased rolipram-sensitive cAMP-specific phosphodiesterase (cAMP-PDE) activity. To understand the mechanisms leading to this activation, the cAMP-PDEs present in the Sertoli cell were characterized and their regulation studied. Comparison of the(More)
This paper examines how low-income, pre-adolescents in a multicultural setting appropriate the popular computer game, The Sims™, for their own learning, social and sense-making activities. The paper documents a variety of educative moments that the children experienced in playing and reflecting about the game and its design. It also suggests features of the(More)
This paper describes novel research that we conducted as part of the Portals project (NSF Grant #CDA-9616990). We examined the roles, functions and strategies that students, teachers, and mentors bring to complex on-line, project-based learning experiences. Data for our study consisted of site observations, interviews, student work samples and videotaped(More)
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