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The nanoscale organization of neurotransmitter receptors regarding pre-synaptic release sites is a fundamental determinant of the synaptic transmission amplitude and reliability. How modifications in… Continue Reading
RAD51 recombinase assembles on single-stranded (ss)DNA substrates exposed by DNA end-resection to initiate homologous recombination (HR), a process fundamental to genome integrity. RAD51 assembly has… Continue Reading
Spectrally resolved fluorescence lifetime imaging microscopy (λFLIM) has powerful potential for biochemical and medical imaging applications. However, long acquisition times, low spectral resolution… Continue Reading
The nanoscale organization of neurotransmitter receptors relative to pre-synaptic release sites is a fundamental determinant of both amplitude and reliability of synaptic transmission. How… Continue Reading
Il est bien admis que la comprehension de la structuration moleculaire a l’interieur des cellules neuronales est essentielle pour apprehender le fonctionnement du cerveau. Pour cette raison, l’etude… Continue Reading
The biochemical activities underlying cell-fate decisions vary profoundly even in genetically identical cells. But such non-genetic heterogeneity remains refractory to current imaging methods,… Continue Reading