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MAIT cells activate dendritic cells to promote T follicular helper cell differentiation and humoral immunity
It is shown that MAIT cells are promising vaccine targets that can be utilised as cellular adjuvants in mucosal vaccines.
Different bacterial and viral pathogens trigger distinct immune responses in a globally invasive ant
Invasive species populations periodically collapse from high to low abundance, sometimes even to extinction. Pathogens and the burden they place on invader immune systems have been hypothesised as a…
Harnessing the Potential of MAIT Cells as Cellular Adjuvants in Mucosal Vaccines
- Kaitlin H. Buick
- Biology, Medicine
Whether mucosal-associated invariant T (MAIT) cells which are found in mucosal tissues, are invariant in nature and have rapid activation, could be exploited as cellular adjuvants in mucosa vaccines is explored.