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Activity of 25-Hydroxylase in Human Gingival Fibroblasts and Periodontal Ligament Cells
TLDR
The activity of 25-hydroxylase was verified in human gingival fibroblasts and periodontal ligament cells, and CYP27A1 was identified as the key 25- hydroxyvitamin D3 synthesis in these cells.
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Elevated plasma calcifediol is associated with aggressive periodontitis.
BACKGROUND Vitamin D is associated with a number of inflammatory diseases and plays a significant role in regulating bone metabolism. Serum calcifediol was demonstrated to be potentially associated…
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Upregulated Leptin in Periodontitis Promotes Inflammatory Cytokine Expression in Periodontal Ligament Cells.
TLDR
Upregulated leptin and OBR in periodontitis stimulated proinflammatory cytokine expression in PDL cells to additionally promote local inflammation.
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Initial periodontal therapy reduced systemic and local 25-hydroxy vitamin D(3) and interleukin-1beta in patients with aggressive periodontitis.
TLDR
25-hydroxy vitamin D(3) and interleukin-1beta levels were systemically and locally reduced in patients with GAgP by initial periodontal therapy.
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Preliminary investigation of the vitamin D pathway in periodontal connective tissue cells
TLDR
It is suggested that the vitamin D pathway exists in hGFs and hPDLCs and plays an important role in immune defense in periodontal soft tissues.
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[Clinical and radiographic evaluation of class III furcation defects in the treatment using autogenous periodontal ligament cells with or without enamel matrix derivatives].
TLDR
The results of this study indicate that class III furcation defects can not be predictably resolved even with the combination of autogenous PDLC and EMD, although they may increase the repair of periodontal tissue in the area of class IIIfurcation defects separately.
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Influence of rs2228570 on Transcriptional Activation by the Vitamin D Receptor in Human Gingival Fibroblasts and Periodontal Ligament Cells
TLDR
The FF-VDR genotype is associated with the most remarkable upregulation of alkaline phosphatase and osteocalcin in hPDLCs.
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Characterization of the Autocrine/Paracrine Function of Vitamin D in Human Gingival Fibroblasts and Periodontal Ligament Cells
TLDR
The expression, activity and functionality of 1α-hydroxylase were detected in human gingival fibroblasts and periodontal ligament cells, raising the possibility that vitamin D acts in an autocrine/paracrine manner in these cells.
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Janus Nanoparticles for Improved Dentin Bonding.
TLDR
It is demonstrated that reactive Janus nanoparticles can strongly enhance the dentin bonding interface without cytotoxicity and may be promising materials to substitute for HEMA in dental adhesives.
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Leptin and its receptor expression in dental and periodontal tissues of primates
TLDR
The expression of the long and also functional form of OBR (OBRb) indicates that leptin has a direct effect on these cells, and it can reasonably infer that leptin and OBR exert effects on defense, mineralization and angiogenesis in dental and periodontal tissues of primates.
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