Kailash R. Biyani

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The buccal region of the oral cavity is an attractive target for administration of the drug of choice. Sustained release formulations have been developed and are gaining in popularity and medical acceptance. To increase bioavailability and prevent first pass metabolism of drug, verapamil hydrochloride was embedded in sustained released buccal patch over(More)
Evaluation of depressive activity of drug extract of Brahmi, Jatamansi & Shankhpushpi and their combined effects were studied on 66 mice of either sex. It was found that combined effect of Jatamansi, Shankhpushpi & Brahmi showed the potent depressiveness in mice. While in individual drug extract, jatamansi exhibited more potent effect than other two drugs.
Ibuprofen is a non-steroidal anti-inflammatory drug with poor water solubility. The most frequent causes of low oral bioavailability are attributed to poor solubility and low permeability. Solid dispersion technique can be used to enhance the solubility; dissolution rate and absorption of several insoluble drugs. The different solid dispersion methods were(More)
Two simple, rapid, precise and accurate spectrophotometric methods have been developed for determination of Amlodipine Besylate (AMB) and Hydrochlorothiazide (HCTZ) by simultaneous equation method and stability study method in combined tablet dosage form. The simultaneous equation method is based on measurement of absorbance at 238 nm and 271 nm as two(More)
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