Characterization of Novel Bacteriophage AhyVDH1 and Its Lytic Activity Against Aeromonas hydrophila
- Yahui Cheng, Dongye Gao, W. Xiao
- BiologyCurrent Microbiology
- 11 November 2020
A novel bacteriophage AhyVDH1, which infects Aeromonas hydrophila 4572, was isolated and its morphology, one-step growth curve, lytic activity, stability under various conditions, and genome were investigated, suggesting its potential therapeutic value in treating A. hydrophILA infections.
A Role for Innexin2 and Innexin3 Proteins from Spodoptera litura in Apoptosis
- T. Liu, Ming Li, Kaijun Luo
- BiologyPLoS ONE
- 30 July 2013
This study showed that Sf9 and Spli221 cells undergo low level apoptosis under normal culture conditions, but not Hi5 cells, which suggests that innexon-promoted apoptosis may be involving the PI3K/Akt signaling pathway.
Characterization of Nonjunctional Hemichannels in Caterpillar Cells
- Kaijun Luo, M. Turnbull
- BiologyJournal of Insect Science
- 18 January 2011
These results demonstrate for the first time the activity of nonjunctional hemichannels in insect cells, as well as pharmacological tools to manipulate them, which will facilitate the further examination of the role of innexins and nonj Junctionine hemich channels in insect cell biology, including paracrine signaling, and comparative studies of mammalian pannexin homologues termed innexin.
Bracovirus Sneaks Into Apoptotic Bodies Transmitting Immunosuppressive Signaling Driven by Integration-Mediated eIF5A Hypusination
- Kaijun Luo
- BiologyFrontiers in Immunology
- 4 November 2021
It is shown that ABs transmitted immunosuppressive signaling, causing recipient cells to undergo apoptosis and dismigration, and suggest that integration-mediated eIF5A hypusination drives extracellular vesicles for continuous immunOSuppression.
Phosphate ion targeted colorimetric and fluorescent probe and its use to monitor endogeneous phosphate ion in a hemichannel-closed cell.
- L. Guo, Jun Feng Zhang, Juyoung Yoon
- Biology, ChemistryAnalytical Chemistry
- 20 January 2015
The study has produced the first fluorescent sensor 1 for endogenous inorganic phosphate and the utility of 1 for measuring Pi release in vitro has been demonstrated and utilized to elucidate the mechanism of Inx3 action in hemichannel-closed Sf9 cells.
Highly selective in vivo imaging of endogenous/exogenous phosphate ion over ATP and PPi.
- Jun Feng Zhang, L. Guo, Jong Seung Kim
- BiologyChemistry - An Asian Journal
- 1 May 2015
The chemodosimeter was designed to function as a highly selective phosphate ion sensor, showing a 91-fold ratiometric fluorescence enhancement and was the first probe able to trace the generation and enrichment of Pi through hemichannel closure in Sf9 cells.
Iron(III)-Selective Chelation-Enhanced Fluorescence Sensing for In Vivo Imaging Applications.
- L. Guo, X. Liu, Jun Feng Zhang
- Biology, ChemistryChemistry - An Asian Journal
- 1 September 2015
A "turn-on" pattern Fe(3+) -selective fluorescent sensor was synthesized and characterized that showed high fluorescence discrimination of Fe(3+) over Fe(2+) and other tested ions. With a 62-fold…
Inhibition of translation initiation factor eIF4A is required for apoptosis mediated by Microplitis bicoloratus bracovirus.
- Shu-Mei Dong, Ji-Hui Cui, Kaijun Luo
- BiologyArchives of Insect Biochemistry and Physiology
- 20 September 2017
Findings suggested that MbBV inhibited the expression of eIF4A, which was required for apoptosis mediated by MbV, which will contribute to biological pest control and enhance the understanding of molecular mechanisms underlying polydnavirus-parasitoid-host interaction.
A polydnaviral genome of Microplitis bicoloratus bracovirus and molecular interactions between the host and virus involved in NF-κB signaling
- Dongshuai Yu, Ya-Bin Chen, Kaijun Luo
- BiologyArchives of Virology
- 13 August 2016
Data show that viral IκB-like transcription does not inhibit host NF-κB/IκB expression, suggesting that transcription of these genes might be regulated by different mechanisms.
A Transcriptome Analysis Suggests Apoptosis-Related Signaling Pathways in Hemocytes of Spodoptera litura After Parasitization by Microplitis bicoloratus
- Ming Li, Zunyu Pang, Kaijun Luo
- BiologyPLoS ONE
- 28 October 2014
A new RNAseq-based comparative analysis of the hemocytes transcriptomes of non-parasitized and parasitized S. litura hemocytes suggests that M. bicoloratus parasitism may regulate host mitochondria to trigger internucleosomal DNA fragmentation and facilitates the identification of immunosuppression-related genes.