Kai Zhang

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Fluorous mixture synthesis minimizes the effort to synthesize small molecule libraries by labeling the molecules rather than the reaction vessels. Reactants are labeled with fluorinated tags and products can later be demixed based on fluorine content. A limit in the number of available tags can be overcome by using binary encoding so that a total of four(More)
A series of novel benzisoselenazolone derivatives bearing 1,3,4-thiadiazole moiety were designed, synthesized and evaluated for their in vitro antiproliferative activities against human cancer cell lines SMMC-7721, MCF-7, A549, and normal cell lines L929 by CCK-8 assay. The bioassay results demonstrated that most of the tested compounds showed potent(More)
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