Learn More
Pair programming is a practice in which two programmers work collaboratively at one computer, on the same design, algorithm, or code. Prior research indicates that pair programmers produce higher quality code in essentially half the time taken by solo programmers. An experiment was run to assess the efficacy of pair programming in an introductory Computer(More)
A formal pair programming experiment was run at North Carolina to empirically assess the educational efficacy of the technique in a CS1 course. Results indicate that students who practice pair programming perform better on programming projects and are more likely to succeed by completing the class with a C or better. Student pairs are more self -sufficient(More)
Graphene has emerged as interesting nanomaterials with promising applications in a range of fields including biomedicine. In this work, for the first time we study the long-term in vivo biodistribution of (125)I-labeled nanographene sheets (NGS) functionalized with polyethylene glycol (PEG) and systematically examine the potential toxicity of graphene over(More)
The mechanistic target of rapamycin (mTOR) pathway integrates diverse environmental inputs, including immune signals and metabolic cues, to direct T-cell fate decisions. The activation of mTOR, which is the catalytic subunit of the mTORC1 and mTORC2 complexes, delivers an obligatory signal for the proper activation and differentiation of effector CD4(+) T(More)
Although biomedical applications of carbon nanotubes have been intensively studied in recent years, its sister, graphene, has been rarely explored in biomedicine. In this work, for the first time we study the in vivo behaviors of nanographene sheets (NGS) with polyethylene glycol (PEG) coating by a fluorescent labeling method. In vivo fluorescence imaging(More)
Graphene oxide (GO) and its functionalized derivatives have attracted great attention in biomedicine in recent years. A number of groups including ours have studied the in vivo behaviors of functionalized nano-graphene after intravenous injection or inhalation, and uncovered the surface coating & size dependent biodistribution and toxicology profiles for(More)
Photothermal therapy as a physical treatment approach to destruct cancer has emerged as an alternative of currently used cancer therapies. Previously we have shown that polyethylene glycol (PEG) functionalized nano-graphene oxide (nGO-PEG) with strong optical absorption in the near-infrared (NIR) region was a powerful photothermal agent for in vivo cancer(More)
In this paper we propose cloud-based demand response (CDR), a novel demand response architecture for fast response times in large scale deployments. The proposed architecture is in contrast to master/slave based demand response where the participants directly interact with the utility using host address-centric communication. CDR leverages data-centric(More)
In this paper, we propose a new linear programming formulation for the decoding of general linear block codes. Different from the original formulation given by Feldman, the number of total variables to characterize a parity-check constraint in our formulation is less than twice the degree of the corresponding check node. The equivalence between our new(More)
The mechanisms that regulate T cell quiescence are poorly understood. We report that the tumor suppressor Tsc1 established a quiescence program in naive T cells by controlling cell size, cell cycle entry and responses to stimulation of the T cell antigen receptor. Abrogation of quiescence predisposed Tsc1-deficient T cells to apoptosis that resulted in loss(More)