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  • Ines C. Forstenlehner, Johann Holzmann, Kai Scheffler, Wolfgang Wieder, Hansjörg Toll, Christian G. Huber
  • Chemistry, Medicine
  • Analytical chemistry
  • 2014 (First Publication: 7 January 2014)
  • The characterization of proteins modified with poly(ethylene glycol) (PEG), such as recombinant human granulocyte-colony stimulating factor (PEGylated rhG-CSF or pegfilgrastim), by electrosprayContinue Reading
  • Florian Füssl, K. B. Cook, Kai Scheffler, Amy Erdman Farrell, Stefan Mittermayr, Jonathan Bones
  • Chemistry, Medicine
  • Analytical chemistry
  • 2018 (First Publication: 3 April 2018)
  • Charge variant analysis (CVA) of monoclonal antibodies (mAbs) using cation exchange chromatography is routinely used as a fingerprint of the distribution of posttranslational modifications present onContinue Reading
  • Florian Füssl, Anne Trappe, K. B. Cook, Kai Scheffler, Oliver M Fitzgerald, Jonathan Bones
  • Medicine, Biology
  • mAbs
  • 2019 (First Publication: 2 January 2019)
  • Charge variant analysis is a widely used tool to monitor changes in product quality during the manufacturing process of monoclonal antibodies (mAbs). Although it is a powerful technique for revealingContinue Reading
  • Ewald T J van den Bremer, Aran F Labrijn, +6 authors Rob N de Jong
  • Chemistry, Medicine
  • Analytical chemistry
  • 2017 (First Publication: 17 October 2017)
  • Bispecific antibodies (bsAbs) are one of the most versatile and promising pharmaceutical innovations for countering heterogeneous and refractory disease by virtue of their ability to bind twoContinue Reading