Kahori Kinoshita

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Stage-specific embryonic antigen-3 (SSEA-3)-positive multipotent mesenchymal cells (multilineage differentiating stress-enduring [Muse] cells) were isolated from cultured human adipose tissue-derived stem/stromal cells (hASCs) and characterized, and their therapeutic potential for treating diabetic skin ulcers was evaluated. Cultured hASCs were separated(More)
BACKGROUND Hyaluronic acid (HA) fillers have become the most popular tool for wrinkle treatment and volumization, although HA is generally absorbed within 6-12 months and requires repeated treatments to maintain the effects. METHODS HA was injected onto the bone for volumization with a small 30-gauge needle to examine the long-lasting effects. Of the 63(More)
Although various injection techniques of hyaluronic acid (HA) filler for facial rejuvenation have been developed, correction of deep wrinkles/grooves, such as the nasolabial fold (NLF), with intradermal or subdermal injections remains difficult. We tested the intradermal HA injection method to place multiple HA struts by (1) inserting a small needle(More)
BACKGROUND Hyperbaric oxygenation has been used for various purposes, but its clinical application is limited due to its pulmonary toxicity. We evaluated the therapeutic value of normobaric hyperoxygenation (NBO) for vascularized and nonvascularized tissue transplantation. METHODS Tissue oxygen partial pressure (PtO2) was measured for various organs in(More)
Heatstroke is considered an important condition that may contribute to endothelial cell damage. The aim of this study was to assess temporal profiles of the cytokine (IL-6 and IL-8) and mRNA production when endothelial cells undergo higher temperature stimuli. In the first group, human umbilical vascular endothelial cells (HUVECs) were cultured at 4(More)
The present study was undertaken to assess the metabolism of radiolabeled pregnenolone in the placenta throughout pregnancy in organ culture. The product generated from pregnenolone was only progesterone regardless of the weeks of gestation. The amount of progesterone formed by the placenta was 5.60 +/- 0.15 x 10(-11) moles/mg protein/hour in the 1st(More)
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