Kaavya Narasimhalu

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BACKGROUND The utility of poststroke cognitive status, namely dementia, cognitive impairment no dementia (CIND), mild cognitive impairment (MCI), and no cognitive impairment (NCI), in predicting dementia has been previously examined. However, no studies to date have compared the ability of subtypes of MCI and CIND to predict dementia in a poststroke(More)
OBJECTIVE To cocalibrate the Mini-Mental State Examination, the Modified Mini-Mental State, the Cognitive Abilities Screening Instrument, and the Community Screening Instrument for Dementia using item response theory (IRT) to compare screening cut points used to identify cases of dementia from different studies, to compare measurement properties of the(More)
Accurate neuropsychological assessment of older individuals from heterogeneous backgrounds is a major challenge. Education, ethnicity, language, and age are associated with scale level differences in test scores, but item level bias might contribute to these differences. We evaluated several strategies for dealing with item and scale level demographic(More)
OBJECTIVES The safety and efficacy of early acetylcholinesterase inhibitors therapy in patients with cognitive impairment no dementia (CIND) after a cerebrovascular accident have not been examined. In this study, we investigated the safety and efficacy of rivastigmine in cognition, particularly executive function in patients with CIND because of(More)
BACKGROUND/AIMS Our objective was to characterize the cognitive profile of patients with mild Alzheimer's disease (AD) and subcortical ischemic vascular dementia (SIVD) matched using a functional scale. METHODS AD and SIVD were diagnosed using the NINCDS-ADRDA and the criteria proposed by Erkinjuntti et al., respectively. The Clinical Dementia Rating(More)
BACKGROUND Longitudinal neuroimaging studies could provide insights into pathophysiology of cognitive impairment in PD. We examined the role of hippocampal atrophy and cerebral white matter disease as risk factors for mild cognitive impairment and dementia in PD. METHODS Prospective longitudinal study of patients with mild PD in a tertiary neurology(More)
BACKGROUND The incidence of post stroke cognitive impairment (PSCI) and predictive factors for PSCI among patients with acute lacunar infarcts is unclear. OBJECTIVE To study the impact of acute lacunar infarcts and chronic white matter disease in the development of PSCI. METHODS Prospective cohort study of stroke patients attending a tertiary neurology(More)
BACKGROUND AND PURPOSE While recent studies have examined neuroimaging correlates of post-stroke mild cognitive impairment (MCI), no studies have examined neuroimaging correlates of post-stroke subjective cognitive impairment (SCI). METHODS Consecutive patients with magnetic resonance imaging-confirmed acute lacunar strokes at a tertiary institute were(More)
BACKGROUND AD8 is a brief informant interview used to detect early cognitive change. This study evaluated the diagnostic performance of the participant-rated AD8 (p-AD8) in a predominantly Chinese population. METHODS Data on demographics, clinical, and cognitive features were collected from 73 participants with no cognitive impairment (NCI), 27(More)
(2008). Composite scores for executive function items: Demographic heterogeneity and relationships with quantitative magnetic resonance imaging. Abstract Accurate neuropsychological assessment of older individuals from heterogeneous backgrounds is a major challenge. Education, ethnicity, language, and age are associated with scale level differences in test(More)