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We investigated the capacity of murine T lymphocytes, isolated from various lymphoid organs of normal or antigen-primed donors, to produce IL-2 or IL-4 after activation with anti-CD3 or specific antigen. Our results established that T cells resident within lymphoid organs being drained by nonmucosal tissue sites (e.g., axillary, inguinal, brachial lymph(More)
Nitric oxide modulates interleukin-1 ␤ and tumor necrosis factor-␣ synthesis by alveolar macrophages in pulmonary tuberculosis. Tuberculosis (TB) remains a major health problem worldwide. Clinical and pathologic features of TB depend at least in part on the orchestrated secretion of a number of proinflam-matory cytokines, such as tumor necrosis factor(More)
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