KE Grailey

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Introduction Aminoglycoside doses are optimised to ensure adequate peak levels are attained for the desired bactericidal effect. Dose adjustments are increasingly realised to be important in the critical care setting where pharmacokinetics of agents may vary [1]. Variables affecting dose given include patient weight, renal function, dose per unit weight and(More)
Introduction Therapeutic Drug Monitoring (TDM) is an evolving tool used to optimise the administration of antimicrobial agents; which are well documented to have toxic side effects [1]. In combination with increasing antimicrobial resistance and emphasis on cost-efficiency, provision of the optimal dose of antimicrobial therapy is a very attractive(More)
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