Learn More
Metabolic activation of ifosfamide (IFO) leads to the active 4-hydroxy-metabolite and to a substantial liberation of chloroacetaldehyde (CAA). CAA has been presumed responsible for side effects of IFO. We recently have shown cytotoxic effects of CAA against human tumor cells in vitro. The aim of this study was to demonstrate antitumor effects of CAA in(More)
invited speaker: irene Tracey nuffield Professor anaesthetic science & director, oxford centre for fMri of Brain, nuffield department of clinical neurosciences, (head, nuffield division anaesthetics), oxford university, england, uK The ability to experience pain is old and shared across species. It confers an evolutionary advantage and provides a warning of(More)
  • 1