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The Role of Circulating MicroRNA-126 (miR-126): A Novel Biomarker for Screening Prediabetes and Newly Diagnosed Type 2 Diabetes Mellitus
Recent studies suggested an association of endothelial microRNA-126 (miR-126) with type 2 diabetes mellitus (T2DM). In the current study, we examined whether circulating miR-126 is associated withExpand
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In nonfunctional pituitary adenomas, estrogen receptors and slug contribute to development of invasiveness.
CONTEXT Clinical studies suggest that an imbalance in the actions of estrogen receptor (ER)-α and ERβ is associated with invasion of tumors of epithelial origin. Both ER have been detected in theExpand
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Cancer-derived exosomal miR-25-3p promotes pre-metastatic niche formation by inducing vascular permeability and angiogenesis
Cancer-derived exosomes are considered a major driver of cancer-induced pre-metastatic niche formation at foreign sites, but the mechanisms remain unclear. Here, we show that miR-25-3p, aExpand
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Simpler score of routine laboratory tests predicts liver fibrosis in patients with chronic hepatitis B
  • K. Zhou, C. Gao, +7 authors L. Lu
  • Medicine
  • Journal of gastroenterology and hepatology
  • 1 September 2010
Background and Aim:  In recent years, a great interest has been dedicated to the development of noninvasive predictive models to substitute liver biopsy for fibrosis assessment and follow‐up. Our aimExpand
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Associations of prenatal exposure to phenols with birth outcomes.
Many phenols are known to mimic or antagonize hormonal activities and may adversely affect fetal growth. A study of 567 pregnant women was conducted to investigate the relationship between prenatalExpand
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Long-Term Outcome of High-Intensity Focused Ultrasound in Advanced Pancreatic Cancer
Objectives: The aim of this study was to evaluate safety and efficacy of high-intensity focused ultrasound (HIFU) for advanced pancreatic cancer (PC). Methods: Patients with PC TNM stage III or IVExpand
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LncRNA Snhg1, a non-degradable sponge for miR-338, promotes expression of proto-oncogene CST3 in primary esophageal cancer cells
Competing endogenous RNA (ceRNA) is a newly proposed mechanism that describes a crosstalk among lncRNAs, mRNAs and their shared miRNAs. In this study, the role of miR-338-3p (miR-338) in theExpand
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Assessment of fibrosis in chronic liver diseases
  • K. Zhou, L. Lu
  • Medicine
  • Journal of digestive diseases
  • 1 February 2009
The assessment of liver fibrosis provides useful information not only for diagnosis but also for therapeutic decisions. Although liver biopsy is the current gold standard for fibrosis assessment, itExpand
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Predictors of hepatic steatosis in HBeAg-negative chronic hepatitis B patients and their diagnostic values in hepatic fibrosis
Objective: To investigate predictors of hepatic steatosis in HBeAg-negative chronic hepatitis B (CHB) patients and their diagnostic values in hepatic inflammation and fibrosis. Methods: A total ofExpand
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Potential clinical significance of plasma-based KRAS mutation analysis using the COLD-PCR/TaqMan(®) -MGB probe genotyping method.
Despite the improved ability to detect mutations in recent years, tissue specimens cannot always be procured in a clinical setting, particularly from patients with recurrence of tumors or metastasis.Expand
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