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Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated
Summary Cytoplasmic dynein-1 binds dynactin and cargo adaptor proteins to form a transport machine capable of long-distance processive movement along microtubules. However, it is unclear why dynein-1… Expand
Glucose oxidase/colloidal gold nanoparticles immobilized in Nafion film on glassy carbon electrode: Direct electron transfer and electrocatalysis.
- Shuang Zhao, K. Zhang, Y. Bai, W. Yang, Changqing Sun
- Chemistry, Medicine
- 1 October 2006
The direct electron transfer of glucose oxidase (GOD) was achieved based on the immobilization of GOD/colloidal gold nanoparticles on a glassy carbon electrode by a Nafion film. The immobilized GOD… Expand
Concussion in athletics: ongoing clinical and brain imaging research controversies
Concussion, the most common form of traumatic brain injury, proves to be increasingly complex and not mild in nature as its synonymous term mild traumatic brain injury (mTBI) would imply. Despite the… Expand
Progress of Research on Diffuse Axonal Injury after Traumatic Brain Injury
The current work reviews the concept, pathological mechanism, and process of diagnosing of DAI. The pathological mechanism underlying DAI is complicated, including axonal breakage caused by axonal… Expand
Synthesis of few-layer hexagonal boron nitride thin film by chemical vapor deposition.
In this contribution we demonstrate a method of synthesizing a hexagonal boron nitride (h-BN) thin film by ambient pressure chemical vapor deposition on polycrystalline Ni films. Depending on the… Expand
Modulation of cisplatin cytotoxicity and cisplatin-induced DNA cross-links in HepG2 cells by regulation of glutathione-related mechanisms.
- K. Zhang, M. Chew, Er Bin Yang, K. P. Wong, P. Mack
- Medicine, Chemistry
- Molecular pharmacology
- 1 April 2001
Glutathione (GSH), glutathione S-transferase (GST), and glutathione conjugate export pump (GS-X pump) have been shown to participate collectively in the detoxification of many anticancer drugs,… Expand
Effects of different exposure times and concentrations of sodium hypochlorite/ethylenediaminetetraacetic acid on the structural integrity of mineralized dentin.
INTRODUCTION This study tested the null hypothesis that there is no difference between the use of 1.3% NaOCl/17% ethylenediaminetetraacetic acid (EDTA) and 5.25% NaOCl/17% EDTA irrigation regimens on… Expand
Retromer Is Required for Apoptotic Cell Clearance by Phagocytic Receptor Recycling
Corpse-Sorting Machinery Phagocytosis of apoptotic cells is an integral part of the cell death program and plays critical roles in tissue remodeling, suppression of inflammation, and regulation of… Expand
Interaction domains of p62: a bridge between p62 and selective autophagy.
p62 is a multidomain protein that contains different kinds of protein-protein interaction domains, including an N-terminal PB1 domain, a ZZ-type zinc finger domain, a nuclear localization signal… Expand
Comprehensive profiling of protein lysine acetylation in Escherichia coli.
- K. Zhang, Shuzhen Zheng, J. S. Yang, Yue Chen, Z. Cheng
- Medicine, Biology
- Journal of proteome research
- 17 January 2013
Protein lysine acetylation plays a key role in regulating chromatin dynamics, gene expression and metabolic pathways in eukaryotes, and, thus, contributes to diverse cellular processes like… Expand