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Structure of the human voltage-dependent anion channel
The voltage-dependent anion channel (VDAC), also known as mitochondrial porin, is the most abundant protein in the mitochondrial outer membrane (MOM). VDAC is the channel known to guide the metabolicExpand
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Structure and activity of the N-terminal substrate recognition domains in proteasomal ATPases.
The proteasome forms the core of the protein quality control system in archaea and eukaryotes and also occurs in one bacterial lineage, the Actinobacteria. Access to its proteolytic compartment isExpand
  • 108
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Structural Basis of Outer Membrane Protein Biogenesis in Bacteria
In Escherichia coli, a multicomponent BAM (β-barrel assembly machinery) complex is responsible for recognition and assembly of outer membrane β-barrel proteins. The functionality of BAM in proteinExpand
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Mechanism of 2-oxoglutarate signaling by the Synechococcus elongatus PII signal transduction protein
PII proteins control key processes of nitrogen metabolism in bacteria, archaea, and plants in response to the central metabolites ATP, ADP, and 2-oxoglutarate (2-OG), signaling cellular energy andExpand
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Structural analysis of the adaptor protein ClpS in complex with the N-terminal domain of ClpA
In Escherichia coli, protein degradation is performed by several proteolytic machines, including ClpAP. Generally, the substrate specificity of these machines is determined by chaperone components,Expand
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Mechanism of regulation of receptor histidine kinases.
Bacterial transmembrane receptors regulate an intracellular catalytic output in response to extracellular sensory input. To investigate the conformational changes that relay the regulatory signal, weExpand
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  • Open Access
Porins in prokaryotes and eukaryotes: common themes and variations.
Gram-negative bacteria and mitochondria are both covered by two distinct biological membranes. These membrane systems have been maintained during the course of evolution from an early evolutionaryExpand
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  • Open Access
Omp85 from the Thermophilic Cyanobacterium Thermosynechococcus elongatus Differs from Proteobacterial Omp85 in Structure and Domain Composition*
Omp85 proteins are essential proteins located in the bacterial outer membrane. They are involved in outer membrane biogenesis and assist outer membrane protein insertion and folding by an unknownExpand
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Structural analysis of DegS, a stress sensor of the bacterial periplasm
  • K. Zeth
  • Biology, Medicine
  • FEBS letters
  • 2 July 2004
Regulated proteolysis is a key event in transmembrane signalling between intracellular compartments. In Escherichia coli the membrane‐bound protease DegS has been identified as the periplasmic stressExpand
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AAA+ proteins and substrate recognition, it all depends on their partner in crime
Members of the AAA+ superfamily have been identified in all organisms studied to date. They are involved in a wide range of cellular events. In bacteria, representatives of this superfamily areExpand
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