• Publications
  • Influence
A new model for electron flow during anaerobic digestion: direct interspecies electron transfer to Methanosaeta for the reduction of carbon dioxide to methane
Anaerobic conversion of organic wastes and biomass to methane is an important bioenergy strategy, which depends on poorly understood mechanisms of interspecies electron transfer to methanogenicExpand
Methane formation from long-chain alkanes by anaerobic microorganisms
TLDR
En enrichment cultures are used to show that the biological conversion of long-chain alkanes to the simplest hydrocarbon, methane, is possible under strictly anoxic conditions. Expand
Cultivating the uncultured
TLDR
This technique combines encapsulation of cells in gel micro droplets for massively parallel microbial cultivation under low nutrient flux conditions, followed by flow cytometry to detect microdroplets containing microcolonies to enhance understanding of microbial physiology and metabolic adaptation and will provide new sources of microbial metabolites. Expand
Targeted Access to the Genomes of Low-Abundance Organisms in Complex Microbial Communities
TLDR
Genomic reconstruction from targeted cells of uncultured organisms isolated directly from the environment represents a powerful approach to access any specific members of a community and an alternative way to assess the community's metabolic potential. Expand
Tapping into microbial diversity
TLDR
A large number of microorganisms are still only characterized by 'molecular fingerprints' and have resisted cultivation, so the opportunity to investigate the previously inaccessible resources that these microorganisms potentially harbour is exciting. Expand
The microbiome extends to subepidermal compartments of normal skin
TLDR
Results show the microbiota extends within the dermis, therefore enabling physical contact between bacteria and various cells below the basement membrane, and show that normal commensal bacterial communities directly communicate with the host in a tissue previously thought to be sterile. Expand
Establishing microbial composition measurement standards with reference frames
TLDR
The notion of “reference frames” is defined, which provide deep intuition about the compositional nature of microbiome data, which allow reassessment of published relative abundance data to reveal reproducible microbial changes from standard sequencing output without the need for new assays. Expand
Anaerobic Oxidation of o -Xylene, m -Xylene, and Homologous Alkylbenzenes by New Types of Sulfate-Reducing Bacteria
ABSTRACT Various alkylbenzenes were depleted during growth of an anaerobic, sulfate-reducing enrichment culture with crude oil as the only source of organic substrates. From this culture, two newExpand
Transcriptional Regulation of Central Carbon and Energy Metabolism in Bacteria by Redox-Responsive Repressor Rex
TLDR
The comparative genomics approach was utilized to infer candidate Rex-binding DNA motifs and assess the Rex regulon content in 119 genomes from 11 taxonomic groups, identifying more than 50 novel Rex-regulated operons encoding functions that are essential for resumption of the NADH:NAD(+) balance. Expand
Antimicrobials from human skin commensal bacteria protect against Staphylococcus aureus and are deficient in atopic dermatitis
TLDR
Reintroduction of antimicrobial CoNS strains to human subjects with AD decreased colonization by S. aureus, showing how commensal skin bacteria protect against pathogens and how dysbiosis of the skin microbiome can lead to disease. Expand
...
1
2
3
4
5
...