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Upregulation of miR-489-3p and miR-630 inhibits oxaliplatin uptake in renal cell carcinoma by targeting OCT2
  • Lu Chen, Le Chen, +8 authors Lushan Yu
  • Chemistry, Medicine
  • Acta pharmaceutica Sinica. B
  • 8 January 2019
TLDR
It is indicated thatmiR-489-3p and miR-630 function as oncotherapy-obstructing microRNAs by directly targeting OCT2 in RCC. Expand
Assessing cytotoxicity of photosensitized transformation products of 2,4,6‐trinitrotoluene (TNT) and atrazine with freshwater microbial assemblages
TLDR
It is suggested that photosensitized transformation decreased TNT and atrazine cytotoxicity to microbial assemblages in the natural water. Expand
Identification of Darmstoff analogs as selective agonists and antagonists of lysophosphatidic acid receptors.
TLDR
A facile method for the synthesis of potassium salts of Darmstoff analogs constitute a novel class of lysophosphatidic acid mimetics, which are weak inhibitors of autotaxin. Expand
Riboflavin-photosensitized degradation of atrazine in a freshwater environment.
TLDR
The results show that dealkylation and alkyl chain oxidation are involved in the degradation of atrazine. Expand
Evodia alkaloids suppress gluconeogenesis and lipogenesis by activating the constitutive androstane receptor.
TLDR
The effects of two evodia alkaloids, rutaecarpine (Rut) and evodiamine (Evo), on gluconeogenesis and lipogenesis through their activation of the human CAR are investigated and it is suggested that these compounds may have a therapeutic potential for the treatment of hyperglycemia and type 2 diabetes. Expand
Identification of 1-Hydroxypyrene Photoproducts and Study of the Effect of Humic Substances on its Photolysis
Photolysis products of 1-hydroxypyrene (1-HP) were identified by liquid chromatography coupled with mass spectrometry (LC/MS/MS). It was found that the major photoproducts of 1-HP are 1,6-, 1,8-, andExpand
Iron(III) Chloride-Mediated Regio- and Stereoselective Chlorosulfonylation of Alkynes and Alkenes with Sodium Sulfinates
The atom-economic and one-pot regio- and stereoselective addition of sodium arenesulfinates to either alkynes or alkenes can be achieved with an iron(III) chloride hexahydrate [FeCl3⋅6 H2O] catalyticExpand
Thermoresponsive polymers and their biomedical application in tissue engineering - a review.
TLDR
It is concluded, that research of thermoresponsive polymers has made big progress in recent years, especially for PNIPAm since the 1990s, and manifold research possibilities, e.g. in surface fabrication and 3D-printing and further translational applications are conceivable in near future. Expand
Recent Progress on Cellulose-Based Ionic Compounds for Biomaterials.
TLDR
Both polymeric cellulose derivatives and nanocellulose-based compounds synthesized as versatile biomaterials for a large variety of biomedical applications, such as for wound dressings, controlled release, encapsulation of cells and enzymes, and tissue engineering, are separately described, regarding the diverse routes of synthesis and the established and suggested applications. Expand
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