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Disruption of myoglobin in mice induces multiple compensatory mechanisms.
TLDR
Data demonstrate that disruption of myoglobin results in the activation of multiple compensatory mechanisms that steepen the pO( 2) gradient and reduce the diffusion path length for O(2) between capillary and the mitochondria; this suggests that myoglobin normally is important for the delivery of oxygen.
Downregulation of tumor growth and invasion by redox-active nanoparticles.
TLDR
This study is the first to show that CNPs prevent tumor growth in vivo, and the application of redox-active CNPs may form the basis of new paradigms in the treatment and prevention of cancers.
Mechanical properties of the skin of Xenopus laevis (Anura, Amphibia)
TLDR
The skin of X. laevis, although heterogeneous in structure, possesses features similar to those found in tissues with aligned collagen fibers such as tendons or fish skin, however, in anurans, the skin seems to play a more passive mechanical role during locomotion than in fish.
Significance of Nano- and Microtopography for Cell-Surface Interactions in Orthopaedic Implants
TLDR
The principle mechanisms of nano- and microscale cell-surface interactions in vitro for different cell types onto typical orthopaedic biomaterials such as titanium, cobalt-chrome-molybdenum (CoCrMo) alloys, stainless steel (SS), as well as synthetic polymers are elucidated.
Stromal Interaction Molecule 1 (STIM1) Is Involved in the Regulation of Mitochondrial Shape and Bioenergetics and Plays a Role in Oxidative Stress*
TLDR
The data suggest that store-operated Ca2+ entry and STIM1 are involved in the regulation of mitochondrial shape and bioenergetics and play a role in oxidative stress.
Osteoblast differentiation onto different biometals with an endoprosthetic surface topography in vitro.
TLDR
The data show that surface topography and physicochemical properties of biometals influence osteoblast differentiation in vitro, and a sandblasted Ti6Al4V surface showed enhanced osteoblastic differentiation.
Subcellular distribution of raffinose oligosaccharides and other metabolites in summer and winter leaves of Ajuga reptans (Lamiaceae)
TLDR
Apparently, the subcellular distribution of the RFOs differs because they fulfill different functions in plant metabolism during winter, and Raffinose might function in protecting chloroplast membranes during freezing, whereas higher RFO oligomers may exert protective effects on vacuolar membranes.
Hard tissue ablation with a free running Er:YAG and a Q-switched CO2 laser: a comparative study
Abstract.The Er:YAG and the CO2 laser are competitors in the field of hard tissue ablation. The use of Er:YAG lasers (2.94 μm, pulse length τL of 100 to 200 μs) show smaller areas of thermal defects
Epicardium‐Derived Cells Formed After Myocardial Injury Display Phagocytic Activity Permitting In Vivo Labeling and Tracking
TLDR
It is demonstrated that EPDCs formed after MI display strong endocytic activity to take up i.v‐injected labeled nanoemulsions and may be used for the liposomal delivery of substances to further study their reparative potential.
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