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Actions of galanin and some of its analogues on rat isolated gastric fundus *
Summary— The study was undertaken to characterize the effects of porcine galanin (pGal) and some of its analogues on rat gastric fundus muscle strips. pGal, galantide (M15) and pGal(1–14)‐[Abu8]SCY‐IExpand
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Hypotensive drugs, sodium nitroprusside and prazosin inhibit the metabolic rate in rabbits.
1. Thermoregulatory responses (metabolic rate, rectal and ear skin temperatures, respiratory rate) were measured after treatment with two antihypertensive drugs, i.e. when sodium nitroprusside (6Expand
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Galanin, galantide and galanin (1-14)-[alpha-aminobutyric acid8]-scyliorhinin-I: structure dependent effects on the rat isolated gastric fundus.
The study was undertaken using selected pharmacodynamic parameters to describe the effects of porcine galanin(1-29)-NH2; porcine galanin fragments; galantide; porcineExpand
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Sources of activator Ca2+ for galanin-induced contractions of rat gastric fundus, jejunum and colon.
Galanin (Gal) evoked reproducible contractions of isolated rat gastric fundus, colon and jejunum longitudinal strips in concentrations ranging from 1 nM to 3 microM. EC50 of Gal equalled 12.63, 23.27Expand
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Thermoregulatory activity of sodium nitroprusside and arginine vasopressin.
1. Thermal responses to sodium nitroprusside (SNP, 3 mg/kg/hr) and arginine vasopressin (AVP, 3 micrograms/kg) were investigated in normothermic and febrile rabbits (LPS, 1 microgram/kg) at ambientExpand
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Contractile action of galanin analogues on rat isolated gastric fundus strips is modified by tachyphylaxis to substance P.
This study was undertaken to characterize the interaction of porcine galanin (Gal) and some of its analogues with their receptors on rat gastric fundus muscle strips. Gal, galantide (M15) andExpand
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Increased potency of some substituted short peptide analogues in comparison to galanin(1-15)-NH(2)in rat fundus strips.
The activity of short porcine galanin (Gal) analogues was tested in vitro using rat gastric fundus strips. The peptides contracted longitudinal smooth muscle in a concentration-dependent manner withExpand
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Lysine14galanin(1-15)-NH2: a partial agonist at galanin receptors in rat isolated gastric fundus.
The study was undertaken to characterize the effects of the porcine galanin [pGal(1-29)-NH2] analogue [Lys14]pGal(1-15)-NH2 on rat gastric fundus. [Lys14]pGal(1-15)-NH2 is a less potent contractileExpand
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Actions of several substituted short analogues of porcine galanin on isolated rat fundus strips: a structure-activity relationship.
The activity of porcine galanin (Gal) fragments and analogues were tested in vitro using rat gastric fundus strips. The peptides contracted longitudinal smooth muscle in a concentration-dependentExpand
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Pharmacological characterization of the contractile effects of galanin(l‐29)‐NH2, galantide and galanin(l‐14)‐(α‐aminobutyric acid8)scyliorhinin‐I in the rat gastric fundus †
Summary— Porcine galanin (l‐29)‐NH2, galantide (M15) and galanin (l‐14)‐(a‐aminobutyric acid8)‐scyliorhinin‐I used in concentrations of 300, 1,000 and 3,000 nM respectively caused contractions of ratExpand
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