• Publications
  • Influence
Influence of the serotonin transporter gene-linked polymorphic region on the antidepressant response to fluvoxamine in Japanese depressed patients
The presence of the long (l) variant of the serotonin (5-hydroxytryptamine: 5-HT) transporter gene-linked polymorphic region (5-HTTLPR) is reported to be associated with a more favorable and fasterExpand
  • 214
  • 14
Prediction of Antidepressant Response to Milnacipran by Norepinephrine Transporter Gene Polymorphisms
OBJECTIVE: With a multitude of antidepressants available, predictors of response to different classes of antidepressants are of considerable interest. The purpose of the present study was toExpand
  • 96
  • 6
Monoamine oxidase: A gene polymorphism, tryptophan hydroxylase gene polymorphism and antidepressant response to fluvoxamine in Japanese patients with major depressive disorder
Monoamine oxidase A (MAOA) and tryptophan hydroxylase (TPH) are the staple enzymes in the metabolism of serotonin (5-HT). The genetic polymorphisms of these two enzymes might individually alter theExpand
  • 82
  • 6
No association between the serotonergic polymorphisms and incidence of nausea induced by fluvoxamine treatment
We investigated the association between serotonergic polymorphisms and incidence of nausea, which is the most frequent side-effect of selective serotonin reuptake inhibiters (SSRIs), in 66 patientsExpand
  • 50
  • 5
Influence of the tyrosine hydroxylase val81met polymorphism and catechol‐O‐methyltransferase val158met polymorphism on the antidepressant effect of milnacipran
Genetic polymorphisms of the noradrenergic pathway can be factors to predict the effect of antidepressants when their pharmacological mechanisms of action include the noradrenergic system. TheExpand
  • 58
  • 4
Prediction of antidepressant response to milnacipran by norepinephrine transporter gene polymorphisms.
OBJECTIVE With a multitude of antidepressants available, predictors of response to different classes of antidepressants are of considerable interest. The purpose of the present study was to determineExpand
  • 49
  • 4
Postnatal depression in Japanese women. Detecting the early onset of postnatal depression by closely monitoring the postpartum mood.
OBJECTIVES The terminology and definition of mood disturbance during the early postpartum period has yet to be clearly elucidated among clinical practitioners. Criteria for maternity blues have notExpand
  • 112
  • 3
The G196A polymorphism of the brain-derived neurotrophic factor gene and the antidepressant effect of milnacipran and fluvoxamine
Prediction of the response to different classes of antidepressants has been an important matter of concern in the field of psychopharmacology. The purpose of the present study was to investigateExpand
  • 74
  • 3
Clinical survey of a psychiatric mother and baby unit: characteristics of 100 consecutive admissions.
Demographic, obstetric, clinical features and clinical outcome of 100 consecutive admissions to a psychiatric mother and baby unit are presented. Referral patterns by health services involved areExpand
  • 124
  • 3
A three‐factor model of the MADRS in major depressive disorder
Major Depressive Disorder (MDD) may be composed of some symptom clusters with distinct neurochemical disturbances, suggesting the importance of the factor analysis of depressive symptoms; however,Expand
  • 56
  • 3