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The mouse RecA-like gene Dmc1 is required for homologous chromosome synapsis during meiosis.
The mouse Dmc1 gene is an E. coli RecA homolog that is specifically expressed in meiosis. The DMC1 protein was detected in leptotene-to-zygotene spermatocytes, when homolog pairing likely initiates.Expand
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Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disorders.
gp130 is a ubiquitously expressed signal-transducing receptor component shared by interleukin 6, interleukin 11, leukemia inhibitory factor, oncostatin M, ciliary neurotrophic factor, andExpand
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Group III metabotropic glutamate receptor activation suppresses self‐replication of undifferentiated neocortical progenitor cells
We evaluated the possible functional expression of metabotropic glutamate receptors (mGluRs) by neural progenitors from embryonic mouse neocortex. Constitutive expression was seen with group I, II,Expand
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MN/CA IX/G250 as a potential target for immunotherapy of renal cell carcinomas
The monoclonal antibody G250 (mAbG250) raised against a human renal cell carcinoma (RCC) has been shown to react with a large number of RCCs. Recently, G250 antigen was isolated and found to beExpand
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Transcriptional regulation of the adenovirus E1A gene.
Two distinct classes of the regulatory sequences have been identified in eukaryotic transcription systems. Promoter sequences are located close to the transcription initiation site, and enhancerExpand
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Cryptococcal necrotizing fasciitis in a patient after renal transplantation--a case report.
A 50-year-old man, who had received an ABO-incompatible living related preemptive renal transplantation 1 year before, presented with painful lesions on both lower extremities and fever. At first,Expand
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Comparison of Cosmesis and Body Image After Laparoendoscopic Single-Site Versus Conventional Laparoscopic Donor Nephrectomy.
BACKGROUND This study used a questionnaire to objectively assess the body image of donors who underwent conventional laparoscopic donor nephrectomy (L-DN) or laparoscopic single-site donorExpand
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Pentosidine and its deposition in renal tissue in renal transplantation.
BACKGROUND Advanced glycation end products (AGEs) accumulate in lesions of arteriosclerosis, Alzheimer's disease, rheumatoid arthritis, diabetic retinopathy, and diabetic nephropathy. Among AGEs,Expand
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Genetic and immunological basis of autoimmune diabetes in the NOD mouse.
The non-obese diabetic (NOD) mouse is an animal model of human insulin-dependent diabetes mellitus (IDDM). Most NOD mice show insulitis at several weeks of age, and 60-90% of the female mice developExpand
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A novel conception for liver preservation at a temperature just above freezing point.
BACKGROUND It is generally accepted that 0 to 4 degreesC is a suitable temperature for organ preservation. The reason for this is based on the premise that at temperatures below 0 degreesC,Expand
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