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Phenolic antioxidants in some Vigna species of legumes and their distinct inhibitory effects on α-glucosidase and pancreatic lipase activities.
TLDR
Vigna species of legumes are potential source of antioxidant phenolics and also great sources of strong natural inhibitors for α-glucosidase and lipase activities, and showed distinct variations in the inhibition of enzymes associated with hyperglycemia and hyperlipidemia. Expand
Determination of 1-deoxynojirimycin in mulberry leaves using hydrophilic interaction chromatography with evaporative light scattering detection.
TLDR
This method is sufficiently sensitive for determining 1-deoxynojirimycin in mulberry leaves and other related products. Expand
Concordant induction of prostaglandin E2 synthase with cyclooxygenase-2 leads to preferred production of prostaglandin E2 over thromboxane and prostaglandin D2 in lipopolysaccharide-stimulated rat
TLDR
Rat peritoneal macrophages were stimulated with lipopolysaccaride for various periods and their ability to convert exogenous arachidonic acid to various prostanoids was examined, demonstrating LPS-dependent increase in PGE2 synthase activity that was degenerated by pretreatment with actinomycin D or cycloheximide. Expand
Structure-activity relations of inhibitory effects of various flavonoids on lipopolysaccharide-induced prostaglandin E2 production in rat peritoneal macrophages: comparison between subclasses of
TLDR
The results suggest that the C2-C3 double-bond and 4-oxo functional group of the C-ring are important factors for the high inhibition activities of flavonoids as anti-inflammatory compounds. Expand
EFFECTS OF DRYING METHOD ON PHYSICOCHEMICAL AND FUNCTIONAL PROPERTIES OF SOY PROTEIN ISOLATES
Three soy protein isolates (SPIs) were obtained by different drying methods, including freeze-drying, spray-drying and vacuum-drying. These SPIs were found to be significantly different in color ofExpand
Orally Administered Bisphenol A Disturbed Antigen Specific Immunoresponses in the Naïve Condition
TLDR
It was found that orally administered BPA increased antigen-specific IFN-γ production of T cells and modified whole antigen presenting cells (APCs) to suppress antigen- specific cytokine production from T cells, suggesting that BPA can augment the Th1-type responses of naïve immune systems. Expand
Simple, selective, and rapid quantification of 1-deoxynojirimycin in mulberry leaf products by high-performance anion-exchange chromatography with pulsed amperometric detection.
TLDR
A simple, selective, and rapid method of high-performance anion-exchange chromatography with pulsed amperometric detection (HPAEC-PAD) to quantify DNJ in mulberry-based food products was developed and suggested that DNJ was heat stable and could be an option for sterilizing mulberries-based products. Expand
Purification and identification of 1-deoxynojirimycin (DNJ) in okara fermented by Bacillus subtilis B2 from Chinese traditional food (Meitaoza).
TLDR
The MS and NMR data showed that the purified alpha-glucosidase inhibitor was 1-deoxynojirimycin (DNJ) with a molecular weight of 163 Da, the first time that DNJ was isolated from foods fermented with Bacillus species. Expand
Flavonoids Inhibit Cell Growth and Induce Apoptosis in B16 Melanoma 4A5 Cells
  • Keiko IWASHITA, Masuko KOBORI, K. Yamaki, Tojiro TSUSHIDA
  • Biology, Medicine
  • Bioscience, biotechnology, and biochemistry
  • 1 January 2000
TLDR
The results demonstrate that isoliquiritigenin and butein inhibit cell proliferation and induce apoptosis in B16 melanoma cells and it seems that the pathway by which the chalcones induce apoptose may be independent of p53 and dependent on proteins of the Bcl-2 family. Expand
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